Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse (CAS 144940-98-7) is a biologically active peptide hormone characterized by the molecular formula C₆₀H₉₀N₁₆O₂₂S₄ and a molecular weight of 1515.74, widely utilized in preclinical research to investigate intestinal fluid-electrolyte homeostasis, natriuretic and diuretic mechanisms, and guanylate cyclase-C (GC-C) receptor signaling pathways in rodent models; this product serves as a critical tool for studying secretory diarrhea, hypertension regulation, and gastrointestinal physiology, offering researchers a reliable reagent for elucidating the molecular basis of renal and intestinal function through targeted in-vitro and in-vivo experimental applications.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Guanylin, rat, mouse
CAS NO.
144940-98-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C₆₀H₉₀N₁₆O₂₂S₄
Molecular Weight
1515.74g/mol 
Purity (RP-HPLC)
≥98%
Solubility

Soluble in appropriate buffers and solvents

Endotoxin≤1.0 EU/mg
Biological Activity
Demonstrates biological activity consistent with guanylin function in rat
Storage Conditions
tore at – 20°C in a dry, stable environment. Protect from light and moisture.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Binds to guanylate cyclase-C (GC-C) receptors in the intestinal epithelium.

Stimulates cyclic GMP production, enhancing fluid secretion and electrolyte transport.
Inhibits inflammation and pathogen adhesion in preclinical studies.

    2.PRODUCT INDICATIONS

    Research Use Only: Intestinal physiology, inflammatory bowel disease (IBD), and diarrheal disorder models.

    Cell-Based Assays: GC-C receptor activation, cGMP signaling pathway analysis.

    Pharmacology Studies: Drug development for GI motility disorders.


    3.CLINICAL EFFICACY OF PRODUCT

    Reduces intestinal fluid loss in chemically-induced diarrhea models.
    Suppresses pro-inflammatory cytokines in colonic tissue cultures.
    Demonstrates dose-dependent activity in rodent GI tract assays.

    4.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
    Professional and Secure Packaging
    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
    We can also customize packaging according to customer needs.
    Shipping Methods 
    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Premium API Oxandrolone Ucinky Manufacturing
May 25, 26
Premium API Oxandrolone Ucinky Manufacturing
Premium API Oxandrolone Ucinky Manufacturing Leading global supplier of high-purity chemical raw materials for pharmaceutical grade Oxandrolone Ucinky, combining precision engineering with industrial scale. 5000 kg Annual Output 120 Countries Served 5 Days Sample Lead Time 99.7 On-Time Delivery Industrial Precision Pure Chemical Synthesis Engineering the future of pharmaceutical intermediates with unmatched stability. Our facility stands as a global leader in the oxandrolone ucinky sector, utilizing CRYOGENIC CRYSTALLIZATION and advanced chromatography to ensure an assay purity exceeding 99.8. We integrate a fully automated closed-loop system that eliminates human error and contamination.
Clinical Benefits and Applications of Oxandrolone Therapy
May 22, 26
Clinical Benefits and Applications of Oxandrolone Therapy
Oxandrolone therapy represents a sophisticated intersection of endocrine science and regenerative medicine, primarily utilized to address muscle wasting and metabolic dysfunction. In the global pharmaceutical landscape, this specific approach to androgen therapy is valued for its unique ability to promote protein synthesis while exhibiting a lower androgenic profile compared to traditional steroids, making it a critical tool for patients recovering from severe trauma or chronic illness. From a clinical perspective, understanding the nuances of oxandrolone therapy is essential for optimizing patient outcomes in weight gain and tissue repair.
Clinical Benefits and Production of Oxandrolone Steroid
May 20, 26
Clinical Benefits and Production of Oxandrolone Steroid
The global pharmaceutical landscape has seen a significant rise in the demand for highly specialized anabolic agents, among which the oxandrolone steroid stands out due to its unique chemical profile and therapeutic versatility. As a modified version of dihydrotestosterone, this compound provides a potent means of addressing muscle wasting and metabolic deficits, making it a critical asset in both clinical rehabilitation and advanced physiological research. Understanding the nuances of this synthetic compound is essential for healthcare providers and researchers alike, as it balances efficacy with a relatively lower androgenic profile compared to other steroids.

If you are interested in our products, you can choose to leave your information here, and we will be in touch with you shortly.