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Guanylin, rat, mouse CAS NO.144940-98-7

Guanylin, rat, mouse (CAS 144940-98-7) is a biologically active peptide hormone characterized by the molecular formula C₆₀H₉₀N₁₆O₂₂S₄ and a molecular weight of 1515.74, widely utilized in preclinical research to investigate intestinal fluid-electrolyte homeostasis, natriuretic and diuretic mechanisms, and guanylate cyclase-C (GC-C) receptor signaling pathways in rodent models; this product serves as a critical tool for studying secretory diarrhea, hypertension regulation, and gastrointestinal physiology, offering researchers a reliable reagent for elucidating the molecular basis of renal and intestinal function through targeted in-vitro and in-vivo experimental applications.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Guanylin, rat, mouse
CAS NO.	144940-98-7
Appearance	White to off-white lyophilized powder
Molecular Formula	C₆₀H₉₀N₁₆O₂₂S₄
Molecular Weight	1515.74g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in appropriate buffers and solvents
Endotoxin	≤1.0 EU/mg
Biological Activity	Demonstrates biological activity consistent with guanylin function in rat
Storage Conditions	tore at - 20°C in a dry, stable environment. Protect from light and moisture.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Binds to guanylate cyclase-C (GC-C) receptors in the intestinal epithelium.

Stimulates cyclic GMP production, enhancing fluid secretion and electrolyte transport.

Inhibits inflammation and pathogen adhesion in preclinical studies.

2.PRODUCT INDICATIONS

Research Use Only: Intestinal physiology, inflammatory bowel disease (IBD), and diarrheal disorder models.

Cell-Based Assays: GC-C receptor activation, cGMP signaling pathway analysis.

Pharmacology Studies: Drug development for GI motility disorders.

3.CLINICAL EFFICACY OF PRODUCT

Reduces intestinal fluid loss in chemically-induced diarrhea models.

Suppresses pro-inflammatory cytokines in colonic tissue cultures.

Demonstrates dose-dependent activity in rodent GI tract assays.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
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Shipping Methods
Main Method: International Air Freight

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