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HCV Core Protein (59-68)

HCV Core Protein (59-68) is a high-purity synthetic peptide representing the HLA-A*0201-restricted cytotoxic T lymphocyte (CTL) epitope of Hepatitis C virus core protein. This 10-amino acid peptide (YLVPGVVALV) corresponds to a key immunogenic region recognized by CD8⁺ T cells, making it essential for studying HCV-specific immune responses, vaccine development, and T cell-based therapies. Manufactured under stringent quality controls with HPLC-verified purity and comprehensive analytical documentation, this product provides researchers with a reliable tool to investigate viral immunology, immune evasion mechanisms, and therapeutic vaccine design.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	HCV Core Protein (59-68)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C50H91N21O12
Molecular Weight	1178.42g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in DMSO, PBS (pH 7-8), or physiological saline.
Endotoxin	< 1.0 EU/mg
Biological Activity	The HLA-A*0201-restricted CTL epitope of the hepatitis C virus core protein can induce HCV-specific CD8⁺ T cell immune responses, and can be used for HCV immunology research, vaccine development, and T cell therapy.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

HCV Core Protein (59-68) functions as an MHC class I-restricted epitope that binds to HLA-A0201 molecules on antigen-presenting cells, forming stable peptide-MHC complexes. These complexes are recognized by T cell receptors on CD8⁺ cytotoxic T lymphocytes, triggering T cell activation, proliferation, and effector functions including cytokine release and cytotoxic activity against HCV-infected cells. The peptide's specific sequence (YLVPGVVALV) contains essential anchor residues that confer high binding affinity to HLA-A0201, making it a dominant target in HCV-specific immune responses and a valuable tool for studying T cell recognition and viral clearance mechanisms.

2.PRODUCT INDICATIONS

HCV Immunology Research: Investigation of HCV-specific T cell responses, immune evasion, and viral persistence mechanisms

Vaccine Development: Evaluation of core protein epitopes for therapeutic and prophylactic vaccine design

T Cell Monitoring: Detection and quantification of HCV-specific CD8⁺ T cells using ELISPOT, intracellular cytokine staining, and MHC tetramer assays

Therapeutic Research: Development of adoptive T cell therapies and immune-based treatments for chronic HCV infection

Immune Repertoire Analysis: TCR sequencing and characterization of HCV-specific T cell receptors

Comparative Virology: Study of cross-genotype immune responses and conserved epitope recognition

3.CLINICAL EFFICACY OF PRODUCT

Sequence Accuracy: Verified 10-amino acid sequence (YLVPGVVALV) corresponding to HCV core protein 59-68

Immunological Activity: Validated in T cell activation assays, MHC binding studies, and immune monitoring applications

Research Reproducibility: Consistent performance across multiple batches and experimental systems

Quality Documentation: Certificate of Analysis provided with purity, mass spec, and biological activity data

Technical Support: Access to application guidance for HCV immunology and T cell research

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.