Histatin 3 (H3)
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Histatin 3 (H3) |
| CAS NO. | |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C178H258N64O48 |
| Amino Acid Sequence | DSHAKRHHGYKRKFHEKHHSHRGY (human Histatin 3 sequence) |
| Molecular Weight | 4062.44g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, dilute acetic acid, or PBS (pH 7.0‑7.4) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Antimicrobial and wound‑healing peptide; exhibits antifungal, antibacterial, and immunomodulatory activities; used in oral biology, dermatology, and infection research. |
| Storage Conditions | Store at –20°C, protected from light and moisture. For long‑term storage, recommend –80°C. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Histatin 3 (H3) exerts its antimicrobial activity by disrupting microbial membranes through electrostatic interactions and pore formation, leading to cell lysis and death. It also exhibits immunomodulatory functions, such as promoting wound healing and modulating inflammatory responses in host tissues.
2.PRODUCT INDICATIONS
This peptide is used in research focused on oral infections (e.g., dental caries, periodontitis), skin infections, wound healing, and antimicrobial drug development. It is also applied in studies of biofilm formation, host‑microbe interactions, and the design of peptide‑based therapeutic agents.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies have demonstrated that Histatin 3 (H3) effectively reduces bacterial and fungal loads in oral and dermal infection models, accelerates wound closure, and enhances tissue repair. These findings support its potential as a lead compound for developing topical or oral formulations in clinical oral‑health and dermatological applications.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
