[D-Phe2,6,Pro3]-LHRH CAS NO.67019-15-2

[D – Phe²,⁶,Pro³] – LHRH is a modified luteinizing hormone – releasing hormone (LHRH) peptide. Its CAS number is yet to be determined by comprehensive chemical database searches. The amino acid sequence features D – phenylalanine at positions 2 and 6 and proline at position 3. The molecular formula and molecular weight are subject to accurate determination through advanced mass spectrometry and elemental analysis methods. This peptide shows great potential in biological research due to its unique structure and possible interactions with the LHRH receptor.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[D-Phe2,6,Pro3]-LHRH
CAS NO.	67019-15-2
Appearance	White to off-white lyophilized powder
Molecular Weight	1193.37g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Commonly soluble in water, It may also show some solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) at low concentrations.
Endotoxin	< 1.0 EU/mg
Biological Activity	The biological activity of [D – Phe²,⁶,Pro³] – LHRH is related to its ability to interact with the luteinizing hormone – releasing hormone receptor. It may act as an agonist or antagonist depending on the specific modifications.
Storage Conditions	Store the product at low temperatures, typically at – 20°C or lower.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

[D – Phe²,⁶,Pro³] – LHRH exerts its effects by binding to the luteinizing hormone – releasing hormone receptor (LHRHR). Once bound, it may initiate a series of intracellular signaling cascades. Depending on its configuration as an agonist or antagonist, it can either stimulate or inhibit the release of luteinizing hormone (LH) and follicle – stimulating hormone (FSH) from the anterior pituitary gland. These hormonal changes can further impact reproductive functions and other related physiological processes.

2.PRODUCT INDICATIONS

Research Applications: It is widely used in academic and industrial research settings for studying the hypothalamic – pituitary – gonadal (HPG) axis. Scientists can use it to explore the regulation of reproductive hormones and the underlying mechanisms of reproductive disorders.

Pharmaceutical Development: In the early stages of drug discovery, [D – Phe²,⁶,Pro³] – LHRH can serve as a lead compound or a tool for developing new drugs targeting reproductive – related diseases, such as infertility, precocious puberty, and hormone – dependent cancers.

3.CLINICAL EFFICACY OF PRODUCT

As a research – grade peptide, its "clinical efficacy" in the traditional sense is not fully established. However, in pre – clinical studies, it has shown promising results in modulating the release of reproductive hormones. For example, in animal models, it has been able to effectively alter LH and FSH levels, which are key indicators of its activity at the LHRHR. Further research, including well – designed clinical trials, is needed to fully evaluate its potential therapeutic efficacy in human patients.

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