VA – β – MSH, Lipotropin – γ, Proopiomelanocortin – derived
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | VA-β-MSH, Lipotropin-γ, Proopiomelanocortin-derived Peptide |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C126H188N36O37S |
| Molecular Weight | 2831.19g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water (≥10 mg/mL), dilute acetic acid, or 0.1M HCl; sparingly soluble in ethanol |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | β-MSH: Potent agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R), induces melanin synthesis and pigmentation, regulates energy homeostasis and anti-inflammatory responses.γ-Lipotropin: Stimulates lipolysis in adipose tissue; precursor to β-endorphin and other bioactive peptides, exhibits weak opioid activity. |
| Storage Conditions | Store at -20°C to -80°C in a desiccated environment. Avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
VA-β-MSH: Acts as a potent agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R). It binds to MC1R on melanocytes to stimulate tyrosinase activity and melanin synthesis, and interacts with MC3R/MC4R in the hypothalamus to regulate energy balance and suppress inflammation.
γ-Lipotropin: Promotes lipolysis in adipocytes by activating hormone-sensitive lipase, releasing free fatty acids into the bloodstream. It also serves as a precursor to β-endorphin, exerting weak opioid effects on the central nervous system.
2.PRODUCT INDICATIONS
Skin pigmentation disorders and photoprotection mechanisms
Obesity and metabolic syndrome pathways
Neuroendocrine regulation of appetite and energy homeostasis
Anti-inflammatory and immunomodulatory responses
Opioid peptide biosynthesis and pain signaling
3.CLINICAL EFFICACY OF PRODUCT
VA-β-MSH: Effective in inducing skin darkening for photoprotection in UV-exposed skin, and reducing inflammation in models of psoriasis and atopic dermatitis.γ-Lipotropin: Shows potential in mobilizing stored fat in animal models of obesity, with implications for lipid disorder therapies.Both peptides are being investigated for their role in regulating stress responses and mood disorders via the POMC pathway.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
