MBP (90-106), phosphorylated

MBP (90-106), phosphorylated is a synthetic peptide fragment derived from the myelin basic protein (MBP) sequence, encompassing residues 90 to 106 and incorporating site-specific phosphorylation modifications. This high-purity, research-grade reagent mimics a key post-translationally modified epitope of MBP and is essential for investigating phosphorylation-dependent processes in myelin structure, function, and the immunopathology of demyelinating diseases.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Myelin Basic Protein (90-106)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C89H141N25O22
Molecular Weight	1913.27g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in deionized water, dilute acetic acid (0.1% v/v) and neutral phosphate buffers (PBS pH 7.0-7.4)
Endotoxin	< 1.0 EU/mg
Biological Activity	Phosphorylated functional epitope of myelin basic protein
Storage Conditions	Store at -20°C in a tightly sealed container under desiccation
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide functions as a biologically relevant phospho-epitope. The phosphorylation at specific serine/threonine residues within the MBP (90-106) region alters its charge, conformation, and molecular interactions. It serves as a specific substrate for studying enzymatic activity (e.g., kinases and phosphatases) and as a precise ligand for binding studies with phospho-specific antibodies, signaling proteins, or other phospho-binding domains, thereby enabling detailed analysis of myelin signaling and stability.

2.PRODUCT INDICATIONS

This product is indicated for advanced research in neurochemistry, molecular immunology, and signal transduction. Primary applications include: studying the role of MBP phosphorylation in myelin assembly and stability, developing and validating phospho-specific antibodies for diagnostic assays, investigating kinase and phosphatase activity in neurological contexts, and exploring how post-translational modifications alter antigenicity in autoimmune models like multiple sclerosis (MS).

3.CLINICAL EFFICACY OF PRODUCT

MBP (90-106), phosphorylated is a specialized research tool, not a clinical therapeutic. Its efficacy lies in its role as a critical reagent for translational research. By enabling precise studies on MBP modification, it contributes to understanding disease mechanisms, identifying potential biomarkers for MS and other disorders, and validating drug targets related to myelin integrity, thereby supporting the preclinical pipeline for novel neuroprotective or immunomodulatory therapies.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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