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[D-Phe7] a-MSH, amide

[D-Phe7] α-MSH, amide is a high-quality modified peptide with enhanced stability and bioactivity. Its specifications (including CAS number, molecular formula, molecular weight, amino acid sequence, and purity) are detailed in the product datasheet. This analogue is widely used in dermatological, metabolic, and endocrine research.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[D-Phe7] α-MSH, amide
CAS NO.
Appearance	White to off-white lyophilized powder
Molecular Formula	C77H109N21O19S
Amino Acid Sequence	Ac-Ser-Tyr-Ser-Met-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Molecular Weight	1664.92g/mol
Purity (RP-HPLC)	≥98.0%
Solubility	Soluble in water and aqueous buffers (e.g., PBS, pH 7.0–7.4)
Endotoxin	< 1.0 EU/mg
Biological Activity	Melanocortin receptor agonist with enhanced stability and prolonged activity compared to native α-MSH; stimulates melanogenesis and modulates inflammatory responses.
Storage Conditions	Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

[D-Phe7] α-MSH, amide functions as a potent melanocortin receptor agonist, primarily targeting MC1R and MC4R. Its D‑amino acid substitution at position 7 improves resistance to enzymatic degradation, leading to prolonged receptor activation and enhanced downstream signaling in pigment formation and energy balance regulation.

2.PRODUCT INDICATIONS

This peptide is utilized in research focused on skin pigmentation disorders, obesity, metabolic syndrome, and inflammatory conditions. It is also applied in studies of neuroendocrine pathways, appetite control, and the development of therapeutic peptides for cosmetic and metabolic applications.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that [D-Phe7] α-MSH, amide effectively promotes melanogenesis, reduces inflammation, and modulates food intake and energy expenditure in animal models. These findings support its potential as a lead compound for treating hypopigmentation, metabolic diseases, and related disorders.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.