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C-Type Natriuretic Peptide, Chicken

C-Type Natriuretic Peptide, Chicken (CNP, Chicken) is a species-specific bioactive peptide belonging to the natriuretic peptide family, with no unique CAS number. It has a molecular formula of C₉₃H₁₅₇N₂₉O₂₉S₃ and a molecular weight of 2241.66 g/mol.As a selective agonist of natriuretic peptide receptor B (NPR-B), it exerts key physiological functions including cGMP production stimulation, vascular tone regulation, cell proliferation control, bone growth modulation, and natriuretic/diuretic effects. Our Chicken CNP is manufactured under strict quality control, ensuring ≥98% purity (RP-HPLC), low endotoxin levels, and stable biological activity, making it an ideal tool for avian physiology research, pharmaceutical R&D, and natriuretic peptide signaling studies.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	C-Type Natriuretic Peptide, Chicken (CNP, Chicken)
CAS NO.	\
Appearance	White to off-white lyophilized powder
Molecular Formula	C₉₃H₁₅₇N₂₉O₂₉S₃
Molecular Weight	2241.66 gg/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water (≥1 mg/mL), PBS buffer (pH 7.2–7.4), and DMSO; slightly soluble in methanol/ethanol
Endotoxin	< 1.0 EU/mg
Biological Activity	Selective agonist of natriuretic peptide receptor B (NPR-B); stimulates cGMP production; regulates vascular tone, cell proliferation, and bone growth; natriuretic and diuretic effects
Storage Conditions	-20°C for long-term storage (stable for 2 years); avoid repeated freeze-thaw cycles; store desiccated
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The biological effects of Chicken C-Type Natriuretic Peptide are primarily mediated through its high-affinity and selective binding to natriuretic peptide receptor B (NPR-B), a transmembrane guanylyl cyclase receptor. Upon binding, it activates the guanylyl cyclase domain of NPR-B, catalyzing the conversion of guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP)—the primary second messenger for CNP signaling.

2.PRODUCT INDICATIONS

Avian physiology research: Investigation of natriuretic peptide signaling in chickens, including fluid-electrolyte balance, vascular regulation, and bone development.

Natriuretic receptor research: Study of NPR-B structure-function relationships, serving as a standard ligand for receptor activation assays and agonist/antagonist screening.

Bone growth and development research: Exploration of CNP-mediated chondrocyte differentiation and its role in skeletal development, supporting orthopedic drug R&D.

3.CLINICAL EFFICACY OF PRODUCT

Chicken C-Type Natriuretic Peptide is currently used primarily in preclinical and avian research, with promising efficacy demonstrated in in vitro and in vivo avian models. In chicken chondrocyte cultures, it has shown significant ability to promote cell differentiation and proliferation, validating its role in bone growth regulation and providing a valuable tool for studying avian skeletal development.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.