Atrial Natriuretic Factor (1-24) (frog) CAS NO.118691-43-3
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Atrial Natriuretic Factor (1‑24) (frog) |
| CAS NO. | 118691-43-3 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C103H165N37O34S3 |
| Amino Acid Sequence | Ser‑Leu‑Arg‑Arg‑Ser‑Ser‑Cys‑Phe‑Gly‑Gly‑Arg‑Ile‑Asp‑Arg‑Ile‑Gly‑Ala‑Gln‑Ser‑Gly‑Leu‑Gly‑Cys‑Asn‑Ser‑Phe‑Arg‑Tyr (frog ANF 1‑24; disulfide bond between Cys⁷ and Cys²³) |
| Molecular Weight | 2561.87g/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water, 0.1 M acetic acid, or phosphate‑buffered saline (PBS) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Natriuretic peptide hormone; binds to natriuretic peptide receptors (NPR‑A/NPR‑B), stimulates cGMP production, and promotes diuresis, natriuresis, and vasodilation. Used in cardiovascular and renal physiology research. |
| Storage Conditions | Store at –20°C (lyophilized) or –80°C (solution). Protect from light and repeated freeze‑thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Atrial Natriuretic Factor (1-24) (frog) functions as a natriuretic peptide hormone that binds to natriuretic peptide receptors (NPR-A and NPR-B). This binding stimulates intracellular cyclic guanosine monophosphate (cGMP) production, leading to vasodilation, increased sodium excretion (natriuresis), and diuresis, thereby helping regulate blood pressure and fluid homeostasis.
2.PRODUCT INDICATIONS
This product is designed for research applications in cardiovascular and renal physiology. It is used to investigate mechanisms of blood pressure control, fluid-electrolyte balance, and the role of natriuretic peptides in heart failure, hypertension, and renal diseases in experimental models.
3.CLINICAL EFFICACY OF PRODUCT
While this peptide is not intended for direct clinical use, it serves as a critical research tool. Studies using Atrial Natriuretic Factor (1-24) (frog) have contributed to understanding the physiological and pathophysiological roles of natriuretic peptides, supporting the development of novel therapeutic strategies for cardiovascular and renal disorders.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
