Prepro-Neuromedin U (104-136) (human)
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Prepro‑Neuromedin U (104‑136) (human) |
| CAS NO. | |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C177H277N47O45 |
| Amino Acid Sequence | H‑Gln‑Tyr‑Phe‑Leu‑Arg‑Pro‑Arg‑Asn‑Ser‑Ala‑Gly‑Tyr‑Leu‑Leu‑Arg‑Glu‑Phe‑Leu‑Gln‑Arg‑Phe‑NH₂ (human NMU prepro‑region residues 104‑136; C‑terminal amidation common) |
| Molecular Weight | 3783.47g/mol |
| Purity (RP-HPLC) | ≥95.0% (can be customized to ≥98.0%) |
| Solubility | Soluble in water, dilute acetic acid, or PBS (pH 7.0‑7.4) |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Precursor‑derived fragment of neuromedin U; activates NMU receptors (NMUR1/NMUR2) and regulates smooth muscle contraction, appetite, stress response, and energy homeostasis. |
| Storage Conditions | Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
Prepro-Neuromedin U (104-136) (human) binds to and activates neuromedin U receptors (NMUR1 and NMUR2), initiating G-protein-coupled signaling pathways that regulate smooth muscle contraction, appetite suppression, and energy homeostasis.
2.PRODUCT INDICATIONS
This peptide is used in preclinical research focused on obesity, metabolic syndrome, gastrointestinal motility disorders, and stress-related physiological responses. It also serves as a tool for investigating neuromedin U signaling in neuroendocrine and cardiovascular systems.
3.CLINICAL EFFICACY OF PRODUCT
In experimental models, Prepro-Neuromedin U (104-136) has demonstrated potent anorexigenic effects and the ability to modulate gastrointestinal smooth muscle activity. These findings support its relevance as a research compound for developing potential therapeutics targeting appetite control and metabolic dysregulation.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
