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Obestatin, rat, mouse

Obestatin (rat, mouse) is a synthetic 23-amino acid peptide hormone derived from the post-translational processing of preproghrelin, sharing its precursor with the appetite-stimulating hormone ghrelin. This research-grade peptide is recognized for its potential role in regulating energy balance and gastrointestinal function, though its biological effects and receptor mechanisms remain an area of active investigation in rodent models.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Obestatin, rat, mouse
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C114H174N34O31
Molecular Weight	2516.87 /mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in deionized water, dilute acetic acid (0.1% v/v) and PBS buffer
Endotoxin	≤1.0 EU/mg
Biological Activity	Endogenous ghrelin-associated peptide; binds to GPR39 receptor with high affinity
Storage Conditions	Lyophilized powder: Long-term storage at -20°C to -80°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The precise mechanism of action for obestatin is complex and not fully elucidated. It was initially proposed to act through the orphan G protein-coupled receptor GPR39 to exert effects opposite to ghrelin, such as suppressing food intake and inhibiting gastric emptying. However, subsequent studies have reported conflicting results, and its interaction with GPR39 remains controversial.

2.PRODUCT INDICATIONS

This product is indicated for basic research in endocrinology, metabolism, and gastroenterology using rat and mouse models. Key applications include: investigating the physiological role of obestatin in appetite regulation and body weight control, studying its effects on gastrointestinal motility and secretion, exploring its potential impact on pancreatic function and cell proliferation, and serving as a reference peptide in assays aimed at characterizing its receptor signaling and biological activity.

3.CLINICAL EFFICACY OF PRODUCT

Obestatin (rat, mouse) is a research tool, and its therapeutic efficacy in humans is not established. Its "efficacy" in the research context is defined by its utility as a probe to understand the complex biology of the ghrelin gene-derived peptides. Studies in rodent models have yielded valuable, albeit sometimes contradictory, data on its metabolic effects.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.