Neurotensin (9-13) CAS NO.60482-96-4
Neurotensin (9-13) CAS NO.60482-96-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Neurotensin (9-13) |
| CAS NO. | 60482-96-4 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C32H52N8O7 |
| Molecular Weight | 660.82/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water (up to 10 mg/mL), dilute acetic acid, or DMSO |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Soluble in water (up to 10 mg/mL), dilute acetic acid, or DMSO |
| Storage Conditions | Store desiccated at -20°C to -80°C; avoid repeated freeze-thaw cycles. Stable for 2–3 years under proper storage. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
This pentapeptide acts as a ligand for neurotensin receptors (NTS1 and NTS2). While its binding affinity is lower than the full-length peptide or the (8-13) fragment, the Tyr-Ile-Leu sequence is the core motif critical for receptor recognition and activation. It binds to the receptor's binding pocket, triggering downstream G protein-coupled signaling, primarily through the Gq pathway.
2.PRODUCT INDICATIONS
This product is indicated for specialized research in neuropharmacology and peptide chemistry, focusing on the molecular basis of ligand-receptor interactions. Key applications include: defining the minimal structural requirements for neurotensin receptor activation in structure-activity relationship (SAR) studies, serving as a scaffold or starting point for the design of novel NT receptor agonists or antagonists, investigating the contribution of the C-terminal tripeptide to overall binding energy and signaling, and as a reference compound in competitive binding assays to map receptor binding sites.
3.CLINICAL EFFICACY OF PRODUCT
Neurotensin (9-13) is a research-grade molecular probe, not a therapeutic. Its "efficacy" is defined by its critical role in fundamental science. By identifying the Tyr-Ile-Leu motif as the core pharmacophore, this fragment has been instrumental in mapping the active site of neurotensin receptors.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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