Urotensin II (Frog)

Urotensin II (Frog) is a premium frog-specific neuropeptide with a defined molecular formula (C₆₉H₉₆N₁₆O₁₉S₂) and molecular weight (1517.76 g/mol). As a professional Urotensin II supplier, we deliver this product with ≥98% purity (RP-HPLC), low endotoxin levels, and intact disulfide bonds, ensuring potent UT receptor agonist activity. Tailored for amphibian physiology, cardiovascular, and comparative biology research, it excels in frog model assays and UT receptor studies. Choose our Urotensin II (Frog) for high-quality support in your amphibian-focused research and translational projects!

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Urotensin II (Frog)
CAS NO.	\
Appearance	White to off-white lyophilized powder
Molecular Formula	C₆₉H₉₆N₁₆O₁₉S₂
Molecular Weight	g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in distilled water (≥ 1 mg/mL), PBS buffer (pH 7.2–7.4, ≥ 1.5 mg/mL), and DMSO (≥ 2 mg/mL)
Endotoxin	< 1.0 EU/mg
Biological Activity	Potent agonist of urotensin II receptor (UT); regulates vascular tone, cardiovascular function, and osmotic balance in frog models; modulates neuronal excitability and inflammatory responses; exhibits species-specific activity with high affinity for frog UT receptors
Storage Conditions	Store at -20°C or below, desiccated in an airtight, light-protected container
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Urotensin II (Frog) exerts its biological effects through high-affinity binding to the urotensin II receptor (UT)—a G-protein-coupled receptor (GPCR) widely expressed in frog vascular tissues, cardiovascular organs, and the central nervous system. The peptide’s frog-specific sequence and dual disulfide bonds optimize conformational stability, ensuring high selectivity and affinity for frog UT receptors, with minimal cross-reactivity to UT receptors of other species.

2.PRODUCT INDICATIONS

UT receptor research: Investigation of UT receptor structure-function relationships in frog models, serving as a standard ligand for receptor activation assays, agonist/antagonist screening, and binding affinity analysis.

Amphibian physiology research: Study of vascular tone regulation, cardiovascular function, and osmotic balance in frogs, supporting exploration of amphibian-specific physiological mechanisms.

Cardiovascular research: Evaluation of the peptide’s role in modulating frog vascular smooth muscle activity, aiding studies on comparative cardiovascular physiology and pathology.

3.CLINICAL EFFICACY OF PRODUCT

Urotensin II (Frog) is widely utilized in amphibian-focused preclinical research, with proven efficacy in both in vitro and in vivo frog models. In frog vascular smooth muscle cell assays, it exhibits potent UT receptor activation, effectively modulating contraction/relaxation responses with sustained activity due to its intact disulfide bonds—ensuring reliable and reproducible experimental results.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.