Tripeptide-29 CAS NO.103192-50-3

Tripeptide-29 is a synthetic tripeptide cosmetic ingredient designed for skin firming, wrinkle reduction, and barrier enhancement, supplied as a high-purity white to off-white lyophilized powder for topical application. It targets the improvement of skin elasticity, reduction of fine lines, and reinforcement of the skin barrier by stimulating key extracellular matrix components and supporting dermal structural integrity, making it a specialized active for achieving a more resilient and youthful skin appearance.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Tripeptide-29
CAS NO.	103192-50-3
Appearance	White to off-white lyophilized powder
Molecular Formula	C12H19N3O5
Molecular Weight	285.3 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. Recommended to dissolve in sterile water to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	Tripeptide‑29 is a synthetic tripeptide used in cosmetic formulations for its reported skin‑firming, anti‑wrinkle, and barrier‑enhancing properties. It is designed to improve skin elasticity, reduce fine lines, and support overall skin resilience.
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Tripeptide-29 acts by upregulating the synthesis of collagen and elastin through the activation of fibroblast proliferation and TGF-β signaling pathways, thereby increasing dermal density and improving skin firmness. It also modulates matrix metalloproteinase (MMP) activity to reduce collagen degradation and enhances the production of key barrier proteins such as filaggrin and involucrin, resulting in improved skin barrier function and overall skin resilience.

2.PRODUCT INDICATIONS

Tripeptide-29 is indicated for research and development of topical cosmetic formulations targeting skin aging, loss of firmness, fine lines and wrinkles, and compromised skin barrier, including firming serums, anti-aging creams, and barrier repair treatments. It is suitable for products aimed at mature skin, photoaged skin, and sensitive skin conditions where barrier reinforcement is desired, as well as for in vitro models evaluating collagen synthesis and barrier function.

3.CLINICAL EFFICACY OF PRODUCT

Clinical evaluations of formulations containing Tripeptide-29 demonstrate significant improvements in skin firmness, elasticity, and reduction in wrinkle depth after 8–12 weeks of topical use, with instrumental measurements confirming increased dermal thickness and improved barrier function. Subjective assessments report a visible reduction in fine lines and enhanced skin smoothness, positioning it as an efficacious cosmetic ingredient for anti-aging and barrier repair formulations, supported by controlled clinical studies.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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