Antioxidant peptide B

Antioxidant Peptide B is a specific synthetic peptide sequence, typically derived from natural protein hydrolysates, engineered for its potent antioxidant and cytoprotective properties. This high-purity, research-grade peptide is designed to neutralize reactive oxygen species (ROS), chelate pro-oxidant metal ions, and protect cells and biological systems from oxidative stress-induced damage. It is a valuable tool for research in biochemistry, cosmetic science, nutraceuticals, and the study of oxidative stress-related pathologies.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Antioxidant Peptide B
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C₅₇H₉₁N₁₇O₁₅
Molecular Weight	1254.47g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water (≥5 mg/mL); soluble in 0.1 M acetic acid; soluble in DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	Inhibits superoxide generation in human neutrophil cell-free systems (IC₅₀ = 47 μM); scavenges free radicals; modulates oxidative stress responses. Used in inflammation, cardiovascular, and antioxidant mechanism research
Storage Conditions	Store at -20°C (short-term, up to 1 year); -80°C (long-term, up to 2 years). Protect from light and moisture; avoid repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Antioxidant Peptide B exerts its protective effects through a combination of direct and indirect antioxidant mechanisms:

Direct Free Radical Scavenging: The peptide's sequence contains specific amino acid residues (e.g., Tyrosine, Tryptophan, Histidine, Cysteine, Methionine) that can directly donate electrons or hydrogen atoms to quench various free radicals, including hydroxyl radicals (•OH), peroxyl radicals (ROO•), superoxide anion (O₂•⁻), and the stable radical DPPH•. This converts the radicals into inert molecules.
Metal Ion Chelation: Key residues, particularly Histidine (His) and possibly acidic amino acids, enable the peptide to chelate transition metal ions like iron (Fe²⁺) and copper (Cu²⁺). This prevents these metals from catalyzing the Fenton reaction, a major source of highly damaging hydroxyl radicals.
Inhibition of Lipid Peroxidation: It can protect cellular membranes by interrupting the chain reaction of lipid peroxidation, stabilizing lipid peroxyl radicals (LOO•).
Upregulation of Endogenous Defenses (Potential): Some antioxidant peptides may enhance the cell's own antioxidant capacity by modulating signaling pathways like the Nrf2/ARE pathway, leading to increased production of enzymes like superoxide dismutase (SOD), catalase, and glutathione peroxidase.

2.PRODUCT INDICATIONS

This product is indicated for a wide range of research applications focused on combating oxidative stress. Key areas include:

Biochemical & Antioxidant Assays: As a standard or test compound in evaluating antioxidant capacity using assays such as ORAC (Oxygen Radical Absorbance Capacity), TEAC, FRAP, DPPH scavenging, and metal chelation assays.
Cosmetic & Skincare Research: As an active ingredient in the development of anti-aging, anti-pollution, and photoprotective formulations (serums, creams) to prevent and repair oxidative damage to the skin caused by UV radiation and environmental stressors.
Nutraceutical & Functional Food Development: Investigating its potential as a bioactive component in dietary supplements and functional foods aimed at promoting systemic health and reducing oxidative stress.
Biomedical Research: Studying its protective effects in cellular models (e.g., neuronal cells, hepatocytes, endothelial cells) and animal models of diseases where oxidative stress is a key contributor, such as neurodegenerative disorders, cardiovascular diseases, diabetes, and inflammatory conditions.
Drug Discovery & Formulation: Serving as a lead compound for designing novel antioxidant therapeutics or as a stabilizing/protective agent in formulations.

3.CLINICAL EFFICACY OF PRODUCT

While Antioxidant Peptide B itself may be in preclinical or early research stages, the efficacy of similar antioxidant peptides is supported by a growing body of evidence:

In Vitro & Preclinical Validation: Strong data from biochemical and cell-based studies demonstrate its ability to reduce oxidative stress markers, protect against cytotoxicity induced by H₂O₂ or other oxidants, and inhibit lipid peroxidation.
Cosmetic Efficacy: Clinical studies on topical formulations containing antioxidant peptides have shown measurable benefits, including:
- Reduction in the appearance of fine lines and wrinkles.
- Improvement in skin elasticity, firmness, and hydration.
- Enhanced protection against environmental skin damage.
Nutraceutical Potential: Oral intake of antioxidant peptides in research models has indicated systemic benefits, such as improved antioxidant status in blood, reduced inflammation, and protection of organs from oxidative damage.
Therapeutic Promise: Research supports the potential of specific antioxidant peptides in mitigating pathology in models of age-related and metabolic diseases, highlighting their promise for future therapeutic development.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.