Brain injury Derived Neurotrophic Peptide(3) BINP
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Brain injury Derived Neurotrophic Peptide(3) BINP |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C62H101N17O19 |
| Molecular Weight | 1388.58g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, PBS, or dilute acetic acid. It is recommended to dissolve in sterile water or buffer to prepare stock solutions for cell culture or in vivo studies. |
| Endotoxin | < 1.0 EU/mg (Typical for research-grade peptides) |
| Biological Activity | BINP-3 is a neurotrophic peptide designed to mimic endogenous factors involved in brain repair. It is used in research to study neuroprotection, neuronal survival, and axonal regeneration following brain injury. |
| Storage Conditions | Store at -20°C or lower. For long-term storage, keep desiccated at -20°C. Upon reconstitution, aliquot and store at -20°C to avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
BINP-3 is believed to exert its neurotrophic effects by interacting with specific cell surface receptors, such as tyrosine kinase receptors, on neurons and glial cells. This interaction is hypothesized to activate key intracellular signaling pathways, including the PI3K/Akt and MAPK/ERK cascades. Activation of these pathways leads to downstream effects that inhibit apoptosis, promote cell survival, and stimulate the expression of genes involved in neuronal growth, synaptic connectivity, and the production of endogenous neurotrophic factors.
2.PRODUCT INDICATIONS
BINP-3 is indicated for preclinical research applications in neuroscience, neurology, and neurotrauma. It is used in in vitro cell culture models (e.g., primary neuronal cultures) to study neuroprotection against excitotoxicity or oxidative stress, and in in vivo rodent models of traumatic brain injury, ischemic stroke, or spinal cord injury to assess its potential to reduce lesion volume, enhance functional recovery, and promote neurogenesis or axonal sprouting.
3.CLINICAL EFFICACY OF PRODUCT
Brain Injury Derived Neurotrophic Peptide-3 is a research-grade experimental compound and has no established clinical efficacy or approval for therapeutic use in humans. Its utility is confined to preclinical proof-of-concept studies. Data generated from such research is essential for validating neurotrophic strategies and may inform the future development of peptide-based or small-molecule therapeutics for brain injury, but BINP-3 itself is not a clinical treatment.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
