Urocortin III, human CAS NO.357952-09-1

Urocortin III, human (CAS NO. 357952-09-1) is a high‑purity synthetic peptide designed for neuroscience, endocrinology, and metabolic research.It serves as a selective ligand for corticotropin‑releasing factor receptors, enabling precise investigation of stress, metabolism, and related physiological pathways.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Urocortin III, human
CAS NO.	357952-09-1
Appearance	White to off-white lyophilized powder
Molecular Formula	C185H307N53O50S2
Molecular Weight	4137.96g/mol
Purity (RP-HPLC)	≥95.0% (can be customized to ≥98.0%)
Solubility	Soluble in water, 0.1 M acetic acid, or PBS (pH 7.0‑7.4)
Endotoxin	< 1.0 EU/mg
Biological Activity	Selective CRF₂ receptor agonist; involved in stress response, anxiety, and energy balance regulation.
Storage Conditions	Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

Urocortin III, human functions by selectively binding to corticotropin‑releasing factor type 2 (CRF₂) receptors, activating intracellular signaling cascades that modulate stress responses, energy balance, and cardiovascular function. This receptor‑specific interaction helps regulate neuroendocrine and autonomic pathways involved in adaptation to physiological challenges.

2.PRODUCT INDICATIONS

This peptide is used in preclinical studies of stress‑related disorders, anxiety, metabolic syndrome, and cardiovascular diseases. It is also applied in drug‑discovery assays targeting CRF₂ receptors and in research exploring the interplay between stress, inflammation, and metabolic homeostasis.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical data demonstrate that Urocortin III, human can attenuate stress‑induced behavioral and physiological changes, improve metabolic parameters, and reduce inflammatory markers in experimental models. These findings support its potential as a lead compound for developing novel therapeutics aimed at stress‑related and metabolic conditions.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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