RF-amide peptide, Drosophila

RF-amide peptide, Drosophila

RF-amide peptide, Drosophila

RF-amide peptide, Drosophila

RF-amide peptide, Drosophila

RF-amide peptide, Drosophila, is a synthetic neuropeptide derived from the fruit fly Drosophila melanogaster, characterized by its C-terminal Arg-Phe-NH2 (RF-amide) motif. This peptide is a key member of the FMRFamide-like peptide (FLP) family and is widely used in entomological and neurobiological research to study the regulation of feeding behavior, muscle contraction, and circadian rhythms in insects.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
RF-amide peptide, Drosophila
CAS NO.
/
Appearance
White to off-white lyophilized powder
Molecular Formula
C58H86N16O15
Molecular Weight
1247.43g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water, PBS, or dilute acetic acid. It is recommended to dissolve in sterile water or buffer to prepare stock solutions for biological assays.

Endotoxin< 1.0 EU/mg (Typical for research-grade peptides)
Biological Activity
RF-amide peptide, Drosophila is a neuropeptide that acts as a ligand for G-protein coupled receptors (GPCRs) in Drosophila melanogaster. It is involved in regulating various physiological processes such as feeding behavior, reproduction, and circadian rhythms.
Storage Conditions
Store at -20°C or lower. For long-term storage, keep desiccated at -20°C. Upon reconstitution, aliquot and store at -20°C to avoid repeated freeze-thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide exerts its biological effects by binding to specific G protein-coupled receptors (GPCRs) in the insect nervous system, such as those encoded by genes like CG5811 and CG10823. This interaction modulates intracellular signaling pathways, leading to the regulation of neuronal excitability and the release of other neurotransmitters, thereby influencing physiological processes like heart rate and gut motility.


2.PRODUCT INDICATIONS

This product is indicated for use in research applications involving the study of insect neuroendocrinology, particularly for investigating the role of RF-amide peptides in the control of feeding, reproduction, and stress responses in Drosophilamodels. It serves as a critical tool for functional assays, receptor binding studies, and behavioral experiments in entomology and comparative physiology.


3.CLINICAL EFFICACY OF PRODUCT

As a research-grade reagent, RF-amide peptide, Drosophila, is not intended for diagnostic or therapeutic use in humans or animals. Its efficacy is demonstrated in preclinical research settings, where it has been shown to effectively modulate neuronal activity and physiological responses in insect models, providing valuable insights into the evolutionary conservation of neuropeptide signaling systems.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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