[Asn76] PTH (64-84), human CAS NO.129449-07-6

[Asn76] PTH (64-84), human is a high-purity synthetic peptide fragment derived from the human parathyroid hormone. This research reagent is designed for studies related to bone metabolism, calcium regulation, and endocrine signaling pathways, offering researchers a specific tool to investigate the biological functions of the PTH C-terminal region.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Asn76] PTH (64-84), human
CAS NO.	129449-07-6
Appearance	White to off-white lyophilized powder
Molecular Formula	C94H163N27O35
Molecular Weight	2231.51g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water or aqueous buffers. For best results, prepare a stock solution in sterile water or PBS and aliquot to avoid repeated freeze-thaw cycles.
Endotoxin	< 1.0 EU/mg (Typical for research-grade peptides)
Biological Activity	Exhibits biological activity consistent with the PTH (64-84) fragment. Specific activity may vary depending on the assay system and experimental conditions.
Storage Conditions	Store lyophilized powder at -20°C or below. For long-term storage, keep at -80°C. Protect from light and moisture. Reconstituted solutions should be stored at -20°C or -80°C in single-use aliquots.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This peptide represents the C-terminal region of PTH, which is distinct from the N-terminal fragment responsible for classical receptor activation. While the full-length PTH activates PTH1R to regulate calcium and bone metabolism, the C-terminal fragments like this one are believed to exert their effects through alternative mechanisms, potentially including receptor-independent pathways or specific binding to yet-unidentified targets.

2.PRODUCT INDICATIONS

This product is strictly intended for scientific research and laboratory use only. It is not approved for human or animal clinical diagnosis or therapy. It is commonly used in biochemical assays, receptor binding studies, and as a standard in immunoassays to detect or quantify PTH-related analytes in experimental settings.

3.CLINICAL EFFICACY OF PRODUCT

As a research-grade reagent, this peptide has no direct clinical efficacy data. Its relevance lies in its role as a tool for understanding PTH biology. Research suggests that C-terminal PTH fragments may have biological activity distinct from the full hormone, but these findings are preliminary and have not been translated into approved clinical applications.

4.DELIVERY & SHIPPING

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