Solnatide CAS NO.259206-53-6

Solnatide CAS NO.259206-53-6

Solnatide CAS NO.259206-53-6

Solnatide CAS NO.259206-53-6

Solnatide CAS NO.259206-53-6

Solnatide is a synthetic cyclic peptide designed to mimic the lectin-like domain of TNF, functioning as a potent activator of alveolar fluid clearance without pro-inflammatory effects. It is formulated as a research-grade inhalation agent to treat life-threatening pulmonary permeability edema, offering a targeted mechanism to restore lung function in acute respiratory distress scenarios. This product is essential for preclinical studies focusing on critical care medicine and lung injury repair.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Solnatide
CAS NO.
259206-53-6
Appearance
White to off-white lyophilized powder
Molecular Formula
C82H119N23O27S2
Molecular Weight
1923.11g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water or aqueous buffers. For best results, prepare a stock solution in sterile water or PBS and aliquot to avoid repeated freeze-thaw cycles.

Endotoxin< 1.0 EU/mg 
Biological Activity
Exhibits biological activity consistent with Solnatide. Specific activity may vary depending on the assay system and experimental conditions.
Storage Conditions
Store lyophilized powder at -20°C or below. For long-term storage, keep at -80°C. Protect from light and moisture. Reconstituted solutions should be stored at -20°C or -80°C in single-use aliquots.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Solnatide works by specifically activating the epithelial sodium channel located on the alveolar epithelial cells in the lungs. This activation increases the reabsorption of sodium and, consequently, water from the alveolar space into the interstitium, effectively reducing pulmonary edema and improving gas exchange by clearing excess fluid from the airspaces.

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2.PRODUCT INDICATIONS

This product is under investigation for clinical use in the management of Acute Respiratory Distress Syndrome (ARDS) and other conditions characterized by pulmonary edema. It is indicated for patients where there is impaired alveolar fluid clearance to help resolve edema and improve oxygenation.

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3.CLINICAL EFFICACY OF PRODUCT

In clinical trials, Solnatide has demonstrated efficacy in improving oxygenation and reducing extravascular lung water in patients with ARDS when administered via inhalation. Studies have shown it to be safe and well-tolerated, with potential to reduce the duration of mechanical ventilation, marking it as a significant candidate for therapeutic intervention in critically ill patients with pulmonary permeability edema.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: Solnatide #AP301 #ENaCActivator #ARDSResearch #PulmonaryEdema #LungInjury #CriticalCareResearch #InhalationPeptide


If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157

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