Opioid receptor antagonist CAS NO.152274-66-3

Opioid receptor antagonist is a class of compounds that competitively bind to opioid receptors, effectively blocking the effects of endogenous and exogenous opioids. This product is widely used in clinical settings for the treatment of opioid dependence, alcohol use disorders, and the management of opioid-induced side effects, offering a non-addictive and safe therapeutic option for patients.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Opioid receptor antagonist
CAS NO.	152274-66-3
Appearance	White to off-white lyophilized powder
Molecular Formula	C44H66N12O7S2
Molecular Weight	939.2/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water, DMSO, and methanol; partially soluble in ethanol
Endotoxin	≤1 EU/mg (as determined by LAL assay)
Biological Activity	High-affinity competitive antagonist at μ-, κ-, and δ-opioid receptors
Storage Conditions	Store at 2–8°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The mechanism of action involves the compound's high affinity for mu and kappa opioid receptors, where it acts as a competitive antagonist. By occupying the receptor binding sites, it prevents opioid agonists from activating the receptors, thereby inhibiting the downstream signaling pathways that lead to euphoria, respiratory depression, and other opioid-related effects, effectively reversing or preventing opioid intoxication.

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2.PRODUCT INDICATIONS

This product is indicated for the treatment of opioid use disorder and alcohol dependence, as well as for the reversal of opioid overdose in emergency situations. It is also used to manage opioid-induced constipation and to mitigate weight gain associated with certain antipsychotic medications, providing a versatile therapeutic approach for substance abuse and metabolic disorders.

3.CLINICAL EFFICACY OF PRODUCT

Clinical studies have demonstrated that this antagonist significantly reduces cravings and relapse rates in patients with opioid and alcohol dependence, while also effectively reversing respiratory depression in overdose cases. Its long-acting formulations provide sustained receptor blockade, enhancing treatment adherence and reducing the risk of overdose fatalities.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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