IGF-I Analog
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | IGF-I Analog |
| CAS NO. | / |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C55H90N14O15S2 |
| Molecular Weight | 1251.53 g/mol |
| Purity (RP-HPLC) | ≥98% purity confirmed by reversed-phase high-performance liquid chromatography (RP-HPLC) |
| Solubility | Soluble in sterile water or PBS (pH 7.2–7.4); reconstitute gently to avoid foaming |
| Endotoxin | ≤0.1 EU/μg as determined by LAL assay |
| Biological Activity | Stimulates cell proliferation and survival in a dose-dependent manner in primary and immortalized mammalian cells |
| Storage Conditions | Store at -20°C protected from light; stable for 24 months when stored properly |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The IGF-I Analog functions by binding to the Type 1 Insulin-like Growth Factor Receptor (IGF-1R) on the cell surface, initiating a cascade of intracellular signaling events. This binding activates the receptor's intrinsic tyrosine kinase activity, leading to the phosphorylation of key substrates such as IRS-1 and IRS-2. This activation triggers downstream pathways, including the PI3K/Akt and MAPK/ERK signaling cascades, which are critical for promoting cell cycle progression, inhibiting apoptosis, and stimulating protein synthesis. The analog's modified structure often results in reduced affinity for IGF-binding proteins (IGFBPs), allowing for greater bioavailability and prolonged receptor activation compared to the native hormone.
2.PRODUCT INDICATIONS
This product is primarily indicated for use in cell culture systems where robust cell growth and maintenance are required. It is widely used in the expansion of primary cells, stem cells, and established cell lines, especially in serum-free or low-serum media formulations. The IGF-I Analog is also employed in research focused on muscle hypertrophy, neuroprotection, and tissue regeneration due to its potent anabolic effects. It serves as a critical reagent in studies investigating metabolic regulation, cancer biology, and developmental processes where IGF signaling plays a central role.
3.CLINICAL EFFICACY OF PRODUCT
In research settings, the IGF-I Analog has demonstrated superior efficacy in promoting nitrogen retention and reversing catabolic states in experimental models. Studies have shown that it can significantly enhance body weight gain and muscle protein synthesis while reducing protein breakdown, making it a powerful tool for investigating conditions associated with muscle wasting or growth deficiencies. Its extended half-life and increased potency allow for sustained biological effects, providing researchers with a reliable means to achieve consistent and reproducible results in both in vitro and in vivo studies.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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