Astragaloside VI CAS NO.84687-45-6
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Astragaloside VI |
| CAS NO. | 84687-45-6 |
| Appearance | White to off-white powder |
| Molecular Formula | C54H92O23 |
| Molecular Weight | 1109.29 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; slightly soluble in water; insoluble in n-hexane |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Potent EGFR activator; modulates MAPK/PI3K-AKT signaling; promotes neural stem cell proliferation & survival; enhances neuroprotection and tissue repair in preclinical models. |
| Storage Conditions | Store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The mechanism of action of Astragaloside VI centers on its ability to activate the Epidermal Growth Factor Receptor (EGFR) and downstream MAPK signaling cascades. By binding to EGFR, it initiates a phosphorylation cascade that promotes cell proliferation and survival. This pathway activation is particularly crucial for neural stem cells (NSCs), where it enhances self-renewal and neurosphere formation. Its efficacy is validated through specific inhibitors like Gefitinib and PD98059, which block these effects, confirming its targeted action on the EGFR/MAPK pathway.
2.PRODUCT INDICATIONS
Astragaloside VI is indicated for research applications related to neuroprotection, wound healing, and post-stroke recovery. It is particularly beneficial for studies involving neural stem cell proliferation, ischemic brain injury models, and chronic wound healing processes. This product is suitable for scientists investigating neurological repair mechanisms, dermatological regeneration, and the molecular basis of stroke complications. Its topical and intravenous administration profiles support its use in both in vitro cell culture and in vivo animal models.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical studies demonstrate that Astragaloside VI significantly ameliorates post-stroke depression and enhances neurological function recovery. In transient cerebral ischemic injury models, treatment with Astragaloside VI accelerates wound closure, reduces pus volume, and promotes angiogenesis. Behavioral tests confirm improvements in spatial learning, memory, and motor function. Its efficacy in upregulating the NRG-1-mediated MEK/ERK pathway highlights its potential as a therapeutic candidate for post-stroke complications and mood disorders associated with brain injury.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Astragaloside VI, Radix Astragali, Neuroprotection, Wound Healing, EGFR Activator, MAPK Signaling, Neural Stem Cells, Post-Stroke Depression, Natural Compound, Research Chemical, Supplier, Manufacturer, Bulk order, Pharmaceutical.
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