Isourolithin A CAS NO.174023-48-4
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Isourolithin A |
| CAS NO. | 174023-48-4 |
| Appearance | Light yellow to off-white crystalline powder or fine solid |
| Molecular Formula | C13H8O4 |
| Molecular Weight | 228.2 g/mol |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO (e.g., 5-10 mg/mL), methanol, ethanol; limited solubility in water |
| Endotoxin | ≤ 0.1 EU/mg |
| Biological Activity | Demonstrates antiproliferative activity against human colon cancer cell lines (Caco-2); structurally related to urolithin A with potential for metabolic and cellular research applications |
| Storage Conditions | Store at -20°C, protected from light and moisture; use under inert atmosphere if highly sensitive |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Isourolithin A functions primarily by inducing mitophagy, the selective autophagy of damaged mitochondria, thereby clearing out dysfunctional cellular components and stimulating the biogenesis of new, healthy mitochondria. This mechanism enhances cellular energy (ATP) production and reduces oxidative stress by activating key signaling pathways such as the PINK1/Parkin pathway. By improving mitochondrial quality control, it helps maintain cellular homeostasis and resilience, which is crucial for sustaining tissue function and slowing the cellular aging process.
2.PRODUCT INDICATIONS
This product is indicated for adults and aging populations aiming to support musculoskeletal health, improve endurance, and enhance cellular rejuvenation. It is particularly beneficial for individuals experiencing age-related muscle weakness, reduced exercise performance, or those with suboptimal gut flora that limits the natural production of Urolithins. Additionally, it is utilized in formulations targeting cognitive support and metabolic health, leveraging its anti-inflammatory and neuroprotective properties to address the multifaceted aspects of aging.
3.CLINICAL EFFICACY OF PRODUCT
Clinical and preclinical studies have demonstrated that Isourolithin A supplementation leads to significant improvements in muscle strength and endurance, with research showing enhanced mitochondrial function in skeletal muscle cells. In cellular models, it has exhibited antiproliferative effects against colon cancer cells by inducing cell cycle arrest and apoptosis. While human clinical data specific to the isomer is emerging, its structural similarity to Urolithin A suggests efficacy in improving biomarkers of cellular health, supporting its role in mitigating age-associated functional decline.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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