Vinaginsenoside R3 CAS NO.156012-92-9

Vinaginsenoside R3 CAS NO.156012-92-9

Vinaginsenoside R3 CAS NO.156012-92-9

Vinaginsenoside R3 CAS NO.156012-92-9

Vinaginsenoside R3 CAS NO.156012-92-9

Vinaginsenoside R3 (CAS NO. 156012-92-9) is a high-purity, rare protopanaxadiol-type ginsenoside. It is a steamed/processed or metabolite derivative of major ginsenosides found in Panax ginseng. This structural transformation often results in enhanced bioavailability and distinct, potentiated biological activity compared to its parent compounds. Vinaginsenoside R3 is a research compound of significant interest due to its reported anti-cancer, anti-inflammatory, neuroprotective, and anti-diabetic properties. It serves as a critical tool for pharmacological research, natural product standardization, and the development of novel ginsenoside-based therapeutics. It is supplied as a white to off-white powder.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Vinaginsenoside R3
CAS NO.
156012-92-9
Appearance
White to off-white lyophilized powder
Molecular Formula
C₅₄H₉₀O₂₄
Molecular Weight
1123.27 g/mol
Purity (RP-HPLC)
≥98%
Solubility
Soluble in methanol, ethanol, DMSO; sparingly soluble in water
Endotoxin
<0.1 EU/mg
Biological Activity
Exhibits potential neuroprotective, anti-inflammatory, and anti-tumor activities in preclinical studies.
Storage Conditions
- Solid: 2–8°C, sealed, dry, protected from light and moisture
- Solution: -80°C (long-term storage, ≤6 months); -20°C (short-term, ≤1 month)
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • Induction of Apoptosis in Cancer Cells: It can trigger programmed cell death via both intrinsic (mitochondrial) and extrinsic pathways. This involves modulation of Bcl-2 family proteins, cytochrome c release, caspase activation, and cell cycle arrest, often by inhibiting pathways like PI3K/Akt/mTOR and NF-κB.

  • Potent Anti-inflammatory Action: It suppresses the production of pro-inflammatory cytokines (e.g., TNF-α, IL-6, IL-1β) and mediators (NO, PGE2) by inhibiting the activation of central inflammatory signaling hubs, primarily the NF-κB and MAPK pathways.

  • Neuroprotection: It may protect neurons from oxidative stress, excitotoxicity, and apoptosis, potentially by modulating neurotransmitter systems, reducing neuroinflammation, and promoting neuronal survival pathways (e.g., PI3K/Akt, Nrf2).

  • Improvement of Insulin Sensitivity & Glucose Metabolism: Like other ginsenosides, it may improve glucose uptake in peripheral tissues and protect pancreatic β-cells, contributing to anti-diabetic effects.

2.PRODUCT INDICATIONS

  • Oncology & Cancer Research: As a potent cytotoxic and pro-apoptotic agent for studying anti-cancer mechanisms, chemoprevention, and adjuvant therapy in various cancer models (e.g., liver, lung, colon, breast).

  • Inflammation & Immunology Research: For investigating new natural compounds for chronic inflammatory and autoimmune diseases.

  • Neuropharmacology: Research in neurodegenerative diseases (Alzheimer's, Parkinson's), stroke, and cognitive impairment.

  • Metabolic Disease Research: Studies on type 2 diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).

  • Natural Product & Ginseng Research: As a high-purity reference standard for the authentication, quantification, and biological evaluation of rare ginsenosides in processed ginseng products (e.g., red ginseng, black ginseng) and in pharmacokinetic/metabolite studies.


3.CLINICAL EFFICACY OF PRODUCT

  • Robust Preclinical Evidence: Strong in vitro and in vivo studies have demonstrated its potent anti-cancer, anti-inflammatory, and other bioactivities in animal models. Rare ginsenosides like Vinaginsenoside R3 are often found to be more active than their major precursors in preclinical assays.

  • Metabolite & Processed Ginseng Relevance: Its formation during steaming (red/black ginseng preparation) or as a human metabolite links it directly to the enhanced pharmacological effects attributed to processed ginseng products, which are clinically used and studied.


  • 4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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