Coffeoyl Tripeptide -1

Coffeoyl Tripeptide -1

Coffeoyl Tripeptide -1

Coffeoyl Tripeptide -1

Coffeoyl Tripeptide -1


Caffeoyl Tripeptide-1 is a high-purity, synthetic active ingredient designed for premium anti-aging and brightening skincare. It is a unique molecular hybrid, formed by covalently linking a specific tripeptide sequence to a caffeic acid molecule—a potent natural antioxidant. This innovative conjugation combines the targeted biological signaling of a peptide with the exceptional free-radical scavenging, anti-inflammatory, and tyrosinase-inhibiting properties of caffeic acid. It provides multi-dimensional efficacy by simultaneously targeting hyperpigmentation, oxidative stress, glycation, and loss of skin firmness, making it an essential active for high-performance serums, creams, and treatments.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Coffeoyl Tripeptide-1
CAS NO.
72957-37-0
Appearance
Off-white to light brown lyophilized powder; faint characteristic odor
Molecular Formula
C₃₀H₃₉N₅O₉
Molecular Weight
629.66 g/mol
Purity (RP-HPLC)
≥95.0%
Solubility
Soluble in DMSO, ethanol, and 1,3-propanediol; slightly soluble in water (≤0.5 mg/mL)
Endotoxin
<0.1 EU/mg
Biological Activity
Antioxidant (scavenges DPPH/ABTS radicals); inhibits matrix metalloproteinases (MMPs); promotes collagen synthesis; protects against UV-induced photoaging; soothes inflammation
Storage Conditions
Lyophilized powder: 2–8°C (short-term, 1 year); -20°C (long-term, 2 years); protect from moisture, light, and repeated freeze-thaw cycles
Stock Location
Stock in USA
MOQ
10g


1.MECHANISM OF ACTION

  • Direct Tyrosinase Inhibition for Brightening: The caffeoyl moiety acts as a potent inhibitor of the enzyme tyrosinase, effectively reducing melanin production at the source. This directly targets and helps fade dark spots, sun spots, melasma, and post-inflammatory hyperpigmentation (PIH).

  • Potent Antioxidant & Anti-Glycation Defense: Caffeic acid is a powerful free radical scavenger (antioxidant), neutralizing reactive oxygen species (ROS) from UV, pollution, and blue light. It also functions as an anti-glycation agent, inhibiting the formation of Advanced Glycation End-products (AGEs) that cross-link collagen and elastin, preventing "sugar sag" and loss of elasticity.

  • Targeted Peptide Signaling for Structural Support: The tripeptide component is designed to deliver specific signals to skin cells (e.g., fibroblasts). It can help upregulate the synthesis of key extracellular matrix (ECM) components like collagen and hyaluronic acid, thereby improving skin density, firmness, and hydration.

  • Anti-inflammatory & Soothing Action: The compound helps calm inflammation, which is beneficial for treating hyperpigmentation and sensitive or reactive skin.

  • 2.PRODUCT INDICATIONS

Brightening & Corrective Treatments: As the core active in serums, creams, and spot treatments for melasma, age spots, uneven skin tone, and post-acne marks.

  • Antioxidant & Anti-Pollution Serums: Essential in daytime formulas and ampoules to provide broad-spectrum protection against environmental stressors (UV, pollution, IR, blue light).

  • Anti-Aging & Firming Products: In formulations targeting fine lines, wrinkles, and loss of elasticity caused by photoaging and glycation.

  • Anti-Glycation ("Anti-Sugar Aging") Skincare: A key ingredient in regimens designed to combat the stiffening and aging of collagen.

  • Preventive & Reparative Eye Care: For treating dark circles and protecting the delicate eye area.


  • 3.CLINICAL EFFICACY OF PRODUCT

    Clinically Proven Brightening: Studies show a significant reduction in melanin index and visible lightening of hyperpigmented areas. Its efficacy in reducing spot size and intensity is validated in controlled trials.
    • Improvement in Skin Radiance & Evenness: Instrumental analysis and expert grading confirm enhanced skin luminosity, clarity, and a more uniform complexion with regular use.

    • Reduction in Signs of Photoaging: Measurable improvement in the appearance of fine lines and wrinkles, along with improved skin firmness and elasticity scores.

    • Enhanced Skin Barrier Function & Hydration: Improvement in skin moisturization and barrier integrity, as measured by corneometry and TEWL.

    • High Consumer Satisfaction & Tolerance: Excellent safety profile and high participant satisfaction scores for overall skin appearance, brightness, and smoothness.

      4.Certificate

      • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

      Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


      We prioritize:

      1.A rigorous quality management system

      2.Batch traceability and stability data

      3.Professional laboratory testing and validation

      4.Compliance with international trade standards


      Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

      5.DELIVERY & SHIPPING

      We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

      Professional and Secure Packaging

      Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

      We can also customize packaging according to customer needs.

      Shipping Methods 

      Main Method: International Air Freight

      We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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      Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

      We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


      Hot Tags: Pentapeptide-25, Anti-aging peptide, Collagen booster, Skin firming, Wrinkle reducer, Cosmetic ingredient, Peptide synthesis, Skincare, CAS 1000313-64-36, Synthetic peptide, Dermal repair, Extracellular matrix, Fibroblast activation, Topical serum, Cosmetic research, High purity peptide, Supplier, Manufacturer, Bulk order, Cosmetic raw materialResearch peptide, Pharmaceutical


      If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510

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