Scopoletin CAS NO.92-61-5

Scopoletin CAS NO.92-61-5

Scopoletin CAS NO.92-61-5

Scopoletin CAS NO.92-61-5

Scopoletin CAS NO.92-61-5

Scopoletin is a high-purity, naturally derived hydroxycoumarin compound extracted from medicinal plants such as Scopolia japonica and Artemisia annua. This white to beige crystalline powder is characterized by its potent multi-target biological activities, including anti-inflammatory, antioxidant, and neuroprotective properties. It serves as a critical reference standard for quality control in herbal medicine and a key research tool in pharmacology for investigating neurodegenerative diseases, metabolic disorders, and cancer mechanisms. The product is supplied with comprehensive analytical documentation, including HPLC purity verification, and is recommended for storage under cool, dry, and light-protected conditions to ensure long-term stability.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Scopoletin
CAS NO.
92-61-5 
Appearance
White to beige crystalline powder
Molecular Formula
C10H8O4
Molecular Weight
192.17 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility

Slightly soluble in water; soluble in DMSO, Methanol, Ethanol, and Chloroform

Endotoxin< [Specify value if available, e.g., 5 EU/mg] (Tested per lot)
Biological Activity
Acetylcholinesterase (AChE) inhibitor; Antioxidant; Anti-inflammatory
Storage Conditions
Store at -20°C, protected from light and moisture; 2 years stability
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Scopoletin exerts its pharmacological effects primarily through the selective and reversible inhibition of key enzymes, including monoamine oxidase B (MAO-B) and acetylcholinesterase (AChE). By blocking MAO-B, it increases striatal dopamine levels, which is crucial for motor function, while its inhibition of AChE enhances cholinergic transmission by preventing the breakdown of acetylcholine. Additionally, it modulates inflammatory responses by suppressing the NF-κB signaling pathway, leading to reduced production of pro-inflammatory cytokines such as TNF-α and IL-6, and exhibits antioxidant activity by scavenging free radicals and upregulating endogenous antioxidant enzymes.

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2.PRODUCT INDICATIONS

This product is indicated for use in scientific research focused on neurological disorders, inflammatory conditions, and metabolic syndrome. It is particularly suitable for researchers studying Parkinson's disease, Alzheimer's disease, and vascular dementia due to its dual action on dopaminergic and cholinergic systems. It is also applied in models of hyperuricemia and gout for its uric acid-lowering effects, in cancer biology for its pro-apoptotic activity against various tumor cell lines, and in immunology for investigating autoimmune diseases like rheumatoid arthritis and inflammatory bowel disease.

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3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies demonstrate that Scopoletin administration significantly ameliorates memory deficits in animal models of cholinergic dysfunction and age-related cognitive decline, improving performance in maze tests and object recognition tasks. In models of inflammation, it reduces edema, pain sensitivity, and inflammatory cell infiltration, while in metabolic studies, it effectively lowers serum uric acid levels and improves insulin sensitivity. Although clinical trials in humans are limited, the robust in vivo data support its potential as a therapeutic agent for cognitive enhancement, pain management, and metabolic regulation, warranting further translational research.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags:Scopoletin, Coumarin, Natural Product, MAO Inhibitor, AChE Inhibitor, Neuroprotective, Anti-inflammatory, Antioxidant, Research Chemical, Phytochemical, Standard, HPLC, 92-61-5, Escopoletin, Gelseminic Acid, Chrysatropic Acid, 6-Methoxyumbelliferone, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553

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