Taurocholic acid CAS NO.81-24-3
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Specification |
| CAS NO. | 52286-59-6 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C₂₆H₄₅NO₇S |
| Molecular Weight | 515.70 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in water, ethanol, DMSO, chloroform, dichloromethane, ethyl acetate; sparingly soluble in non-polar solvents |
| Endotoxin | <0.1 EU/mg |
| Biological Activity | Primary conjugated bile acid; aids in fat digestion and absorption; modulates gut microbiota; exhibits hepatoprotective and anti-inflammatory properties |
| Storage Conditions | Sealed container, stored at -20°C (or 2–8°C for short-term), protected from light, moisture, and air; avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 10g |
1.MECHANISM OF ACTION
Taurocholic acid functions as a potent detergent-like molecule. In the duodenum, it solubilizes lipids into mixed micelles, dramatically increasing the surface area for pancreatic lipase action. It activates the bile acid receptor TGR5 (GPBAR1), influencing glucose metabolism, energy expenditure, and inflammation. As a signaling molecule, it regulates the Farnesoid X receptor (FXR) in the ileum and liver, controlling bile acid synthesis, lipid metabolism, and antimicrobial peptide production, thereby maintaining intestinal barrier function.
2.PRODUCT INDICATIONS
Taurocholic acid is indicated for use in research and diagnostic applications, particularly in studies of bile acid metabolism, cholestasis, and digestive physiology. It is used as a critical reagent in cell culture for hepatocyte and intestinal studies, and as a standard in analytical chemistry (HPLC, MS). In pharmaceuticals, it serves as a reference in drug development targeting FXR and TGR5 pathways for metabolic, liver, and gastrointestinal disorders. It is also utilized in formulations studying fat digestion and absorption.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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