Atractylon CAS NO.6989-21-5

Atractylon, a key sesquiterpene derived from Atractylodesrhizomes (Cangzhu/Baizhu), serves as a high-value botanical active for nutraceutical and pharmaceutical R&D. This natural compound is primarily utilized in research focused on metabolic and inflammatory pathways, offering a multi-target profile that supports liver detoxification, immune regulation, and digestive health. Its broad mechanism makes it a versatile ingredient for developing supplements targeting metabolic syndrome and chronic inflammation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Atractylon
CAS NO.	6989-21-5
Appearance	Colorless to pale yellow oily liquid
Molecular Formula	C₁₅H₂₀O
Molecular Weight	216.32 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in ethanol, ethyl acetate, methanol; insoluble in water
Endotoxin	≤20 EU/mg (or Not applicable / N/A for non-pharmaceutical grade)
Biological Activity	Natural sesquiterpene lactone; exhibits anti-inflammatory, hepatoprotective, antioxidant, and potential anti-tumor properties
Storage Conditions	Store in a cool, dry place away from light and oxygen; recommended temperature: 2-8°C or room temperature (15-25°C)
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Atractylon exerts its effects by modulating key inflammatory signaling pathways, including the suppression of NF-κB and MAPK activation, which subsequently reduces the production of pro-inflammatory cytokines like TNF-α, IL-6, and COX-2. It also demonstrates hepatoprotective action by inhibiting oxidative stress and CYP2E1-mediated toxin metabolism, thereby shielding liver cells from chemical-induced damage. Additionally, its antiviral properties are linked to the regulation of the TLR7/MyD88 pathway, providing a mechanistic basis for its traditional use in respiratory health.

2.PRODUCT INDICATIONS

This ingredient is indicated for formulations targeting liver protection, anti-inflammatory responses, and antiviral support. It is suitable for integration into hepatoprotective nutraceuticals, immune-modulatory supplements for allergic rhinitis or respiratory conditions, and functional foods aimed at improving gastrointestinal disorders. The target audience includes adults seeking natural support for liver detoxification, chronic inflammatory conditions, or general wellness enhancement through herbal-based solutions.

3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies confirm that Atractylon significantly mitigates liver injury markers (ALT, AST) in CCl4-induced models and reduces inflammatory edema and pain responses. In respiratory applications, it has shown efficacy in reducing viral-induced lung injury and allergic inflammation metrics. While human clinical data is still emerging, the robust animal and in vitro data validate its potential for delivering measurable health benefits in well-designed formulations.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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