Sovateltide CAS NO. 142569-99-1

Sovateltide (also known as IRL-1620 or PMZ-1620) is a first-in-class synthetic peptide and selective endothelin B (ETB) receptor agonist. It functions as a potent neuroprotective and neurorestorative agent, designed to address conditions involving ischemic injury and neurological damage. This product is particularly relevant for researchers and pharmaceutical developers focusing on stroke therapy, neonatal encephalopathy, and neurodegenerative disease models, offering a novel mechanism distinct from conventional thrombolytics.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Sovateltide
CAS NO.	142569-99-1
Appearance	White to off-white lyophilized powder
Molecular Formula	C₈₆H₁₁₇N₁₇O₂₇
Molecular Weight	1833.00 g/mol (approximate, based on formula)
Purity (RP-HPLC)	≥95%
Solubility	Soluble in water or dilute acidic solutions (e.g., 0.1% acetic acid); insoluble in organic solvents
Endotoxin	≤1 EU/mg (pharmaceutical grade; research grade may have higher limits)
Biological Activity	Potent activator of erythropoiesis and tissue repair; mimics endogenous erythropoietin effects
Storage Conditions	Store at -20°C, protected from light; lyophilized form stable for 24 months
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide exerts its effects by selectively agonizing endothelin B receptors, which are abundantly expressed on neurons, astrocytes, and vascular endothelial cells. This binding triggers a cascade that enhances cerebral blood flow, reduces apoptosis, and promotes mitochondrial biogenesis. Crucially, it stimulates endogenous neural progenitor cells to differentiate into mature neurons and form new blood vessels, facilitating tissue repair and functional recovery after ischemic insults.

2.PRODUCT INDICATIONS

Sovateltide is indicated for research and development in acute neurological emergencies, including acute ischemic stroke (within 24 hours of onset), neonatal hypoxic-ischemic encephalopathy (HIE), and acute spinal cord injury. It is also being investigated for chronic neurodegenerative conditions like Alzheimer's disease. The target audience includes neurologists, neurosurgeons, neonatologists, and pharmaceutical scientists seeking to develop regenerative therapies beyond the narrow time window of traditional reperfusion treatments.

3.CLINICAL EFFICACY OF PRODUCT

Clinical studies, including Phase II/III trials, have demonstrated that Sovateltide significantly improves neurological outcomes when administered adjunctively with standard care. Data show marked reductions in infarct volume, decreased neurological deficit scores, and improved motor function recovery at 90 days post-stroke. In preclinical models of neonatal HIE and spinal cord injury, it has shown efficacy in reducing tissue damage and promoting functional regeneration, supporting its profile as a promising neuroprotective candidate.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Sovateltide #IRL1620 #PMZ1620 #Neuroprotection #ETBagonist #StrokeResearch #Neuroscience #PeptideResearch

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