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Liquiritin CAS 551-15-5

Liquiritin is a high-purity flavonoid glycoside extracted from licorice root, widely used as a key active ingredient in skin-lightening and anti-aging cosmetics. It is valued for its dual-action profile, combining potent antioxidant activity with significant anti-inflammatory effects, making it a preferred choice for formulators developing gentle yet effective solutions for hyperpigmentation and skin rejuvenation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Liquiritin
CAS NO.	551-15-5
Appearance	Yellow to light brown powder
Molecular Formula	C21H22O9
Molecular Weight	418.39 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in ethanol, DMSO, methanol; slightly soluble in water
Endotoxin	≤ 10 EU/mg (if applicable for injectable/biotech use)
Biological Activity	Stimulates collagen synthesis, enhances skin elasticity, supports dermal remodeling
Storage Conditions	Store at 2–8°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The compound primarily functions as a competitive inhibitor of the aldo-keto reductase family 1 member C1 (AKR1C1) enzyme and a modulator of tyrosinase activity, directly interfering with the melanin synthesis pathway to reduce skin pigmentation. Simultaneously, it exerts its effects by scavenging reactive oxygen species (ROS) and downregulating key inflammatory mediators such as NF-κB, thereby protecting skin cells from oxidative stress and UV-induced damage while promoting a more even skin tone.

2.PRODUCT INDICATIONS

This ingredient is specifically indicated for inclusion in a wide range of cosmeceutical formulations, including whitening serums, age-spot correctors, anti-redness creams, and post-inflammatory hyperpigmentation treatments. It is particularly suitable for individuals with sensitive or photo-damaged skin seeking a gentle alternative to harsh chemical lightening agents, as well as for R&D teams formulating natural-based skincare products with clinically proven efficacy.

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3.CLINICAL EFFICACY OF PRODUCT

Preclinical and clinical studies have demonstrated that topical application of Liquiritin leads to a visible reduction in melanin index and significant lightening of hyperpigmented lesions, including melasma and sunspots, within 4 to 8 weeks of regular use. Research also confirms its ability to improve skin barrier function, enhance hydration levels, and provide robust protection against UVB-induced erythema, validating its role as a multifunctional active for comprehensive skin health.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Liquiritin #CAS551155 #LicoriceExtract #SkinWhitening #TyrosinaseInhibitor #AntioxidantFlavonoid #CosmeticRawMaterial #HyperpigmentationTreatment #NaturalBrightening #LicoriceGlycoside

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