Terlipressin Acetate CAS NO.14636-12-5
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Terlipressin Acetate |
| CAS NO. | 14636-12-5 |
| Appearance | White to off – white lyophilized powder |
| Molecular Formula | C52H74N16O15S2 |
| Molecular Weight | 1227.37 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water (reconstituted solution); slightly soluble in methanol |
| Endotoxin | ≤10 EU/mg |
| Biological Activity | Potent V1 receptor agonist; reduces portal hypertension, improves renal perfusion in HRS |
| Storage Conditions | Store at 2–8 °C, protected from light; avoid freeze – thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The pharmacological action centers on selective agonism of vasopressin V1 receptors located on vascular smooth muscle, with significantly higher affinity for V1 over V2 receptors. Upon administration, it induces potent vasoconstriction of splanchnic arteries, which redirects blood flow away from the gut and into the systemic circulation. This mechanism reduces portal venous inflow and pressure, thereby controlling bleeding from esophageal varices, while simultaneously increasing effective arterial blood volume and renal perfusion pressure to reverse functional kidney impairment in HRS.
2.PRODUCT INDICATIONS
This product is clinically approved for the emergency treatment of bleeding esophageal varices and type 1 hepatorenal syndrome in patients with advanced liver cirrhosis. It is also investigated for use in norepinephrine-resistant septic shock and other forms of distributive shock due to its vasoconstrictive and anti-inflammatory properties. The target user population includes hepatologists, critical care specialists, and hospital pharmacies managing acute care settings where rapid control of portal hypertensive hemorrhage or reversal of renal dysfunction is required.
3.CLINICAL EFFICACY OF PRODUCT
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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