BNP-32 ,porcine CAS NO.117345-87-6

Porcine BNP-32 (brain natriuretic peptide, 32-amino-acid porcine isoform) is a natriuretic peptide structurally analogous to human BNP-32, serving as a critical research tool for studying cardiac function, heart failure diagnostics, and neurohormonal regulation. It exhibits high selectivity for natriuretic peptide receptors (NPR-A/B), driving cyclic guanosine monophosphate (cGMP)-dependent signaling to modulate fluid homeostasis, vascular tone, and myocardial remodeling. With preserved biological activity relative to human BNP-32, it is ideal for translational cardiovascular research, including species-specific disease modeling and peptide-based therapy development, making it a valuable reagent for academic and biotech applications focused on heart health and biomarker validation.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	BNP-32 ,porcine
CAS NO.	117345-87-6
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₄₉H₂₅₀N₅₂O₄₄S₃
Molecular Weight	3495.9g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in water, 0.1 M acetic acid, or 10% DMSO solution
Endotoxin	<1 EU/mg
Biological Activity	Potent natriuretic, vasodilatory, and anti-fibrotic activity via activation of NPR-A receptor, increasing cGMP levels; used for cardiac function research, heart failure diagnostics, and neurohormonal regulation studies
Storage Conditions	Store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This product is indicated for preclinical research in cardiovascular science, including (1) validating cardiac biomarkers in porcine models of heart failure, hypertension, or myocardial infarction; (2) studying neurohormonal feedback mechanisms in fluid overload and pressure overload conditions; (3) screening therapeutic agents targeting natriuretic peptide pathways; and (4) developing diagnostic assays (e.g., ELISA, immunoassays) for porcine or cross-species BNP detection. It supports applications in basic research, drug discovery, and translational medicine, particularly for teams investigating species-specific cardiac physiology or peptide therapeutics for cardiovascular diseases.

2.PRODUCT INDICATIONS

In preclinical porcine models of heart failure, BNP-32 administration demonstrates dose-dependent reductions in left ventricular end-diastolic pressure, pulmonary capillary wedge pressure, and systemic vascular resistance, alongside improved cardiac output and renal sodium excretion. These effects correlate with reduced myocardial hypertrophy, fibrosis, and inflammation, mirroring human BNP-32’s cardioprotective benefits. While clinical efficacy in humans requires further study, porcine BNP-32’s structural and functional homology to human BNP-32 validates its use as a surrogate for exploring human cardiac pathophysiology and therapeutic responses, providing robust data for translational research and potential peptide-based interventions.

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3.CLINICAL EFFICACY OF PRODUCT

Explore Porcine BNP-32 (CAS 117345-87-6) for cutting-edge cardiovascular research—ideal for cardiac biomarker validation, heart failure modeling, and neurohormonal pathway studies. Our high-purity peptide reagent supports preclinical assays, drug screening, and diagnostic assay development with species-specific relevance to porcine (and cross-species) cardiac physiology.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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