[Tyr0]-C-Peptide (dog) CAS NO.101135-67-5

[Tyr⁰]-C-Peptide (dog) is an N-terminally tyrosine-modified variant of the endogenous connecting peptide, specifically designed for enhanced immunodetection and metabolic research in canine models. Unlike standard C-peptide, this modification facilitates efficient radiolabeling (e.g., with ¹²⁵I) and improves antibody recognition, making it an indispensable tool for precise quantification of β-cell function. It is particularly suited for researchers developing canine-specific immunoassays, studying insulin secretion kinetics, and investigating diabetes pathophysiology in veterinary and comparative endocrinology.

support@huanqiukeji9.com

Send Email

Download

TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[Tyr⁰]-C-Peptide (dog)
CAS NO.	101135-67-5
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₄₆H₂₃₄N₃₈O₅₁
Molecular Weight	3527.9g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in water or acidic aqueous solutions (e.g., 0.1% acetic acid); insoluble in organic solvents without denaturation
Endotoxin	≤1 EU/mg (LAL test)
Biological Activity	Soluble in water or acidic aqueous solutions (e.g., 0.1% acetic acid); insoluble in organic solvents without denaturation
Storage Conditions	Store at –20°C, protected from light and moisture; avoid freeze-thaw cycles
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide functions as an equimolar byproduct of proinsulin processing, released alongside insulin from pancreatic β-cells. While it exhibits weak insulin-like signaling, its primary research utility lies in its metabolic stability—unlike insulin, it undergoes negligible hepatic extraction, allowing peripheral levels to accurately reflect pancreatic secretion rates. The Tyr⁰ modification does not alter this core pharmacokinetic profile but provides a chemical handle for tracer studies, enabling real-time tracking of C-peptide clearance and distribution in experimental settings.

2.PRODUCT INDICATIONS

This product is indicated for preclinical research focused on canine diabetes mellitus, β-cell mass assessment, and insulin resistance modeling. It serves as a critical standard for calibrating ELISA kits and radioimmunoassays (RIA) to monitor residual insulin secretion in diabetic dogs. Researchers in veterinary pharmacology and comparative medicine utilize it to evaluate islet transplantation outcomes, screen antidiabetic drugs, and validate diagnostic protocols for spontaneous canine diabetes.

upload/attachment/image/202604/23/1776907425b2f5e0341a4346f67cbbb0898ce470da_local.png

3.CLINICAL EFFICACY OF PRODUCT

In experimental applications, [Tyr⁰]-C-Peptide (dog) demonstrates high diagnostic accuracy for quantifying endogenous insulin secretion, with linear detection ranges suitable for both basal and glucose-stimulated conditions. Studies confirm its reliability as a surrogate marker for β-cell function, showing strong correlation with insulinoma presence and treatment response in canine patients. Its Tyr⁰ modification significantly enhances assay sensitivity and specificity, reducing background interference in complex biological matrices like serum and plasma.

upload/attachment/image/202604/23/1776907452261395db38b44934a51d3b85a8344ffd_local.png

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

upload/attachment/image/202603/30/17748488791d02f82103a700e61eeafa024a96f6ff_local.jpg

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Tyr0CPeptideDog, #CanineCPeptide, #DogInsulin, #BetaCellFunction, #VeterinaryDiabetes, #MetabolismResearch, #ConnectingPeptide, #ResearchPeptide

If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85244969439