ACTH (1-14) CAS NO.149635-73-4

ACTH (1-14) is a synthetic peptide fragment of adrenocorticotropic hormone (ACTH), designed to activate the hypothalamic – pituitary – adrenal (HPA) axis. It is suitable for researchers studying endocrine regulation, stress responses, and adrenal function, as well as for pharmaceutical development focused on glucocorticoid – related therapies. With high purity and reliable activity, it enables precise investigation of ACTH – mediated biological mechanisms.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	ACTH (1-14)
CAS NO.	149635-73-4
Appearance	White to off – white powder
Molecular Formula	C₇₇H₁₆₉N₂₁O₂₀S
Molecular Weight	1680.9g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water, dilute acid; slightly soluble in methanol, insoluble in ethanol, acetone, chloroform
Endotoxin	≤1 EU/mg
Biological Activity	Stimulates adrenal cortex to secrete glucocorticoids, regulates stress response, metabolic processes
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

ACTH (1-14) binds to melanocortin receptor 2 (MC2R) on adrenal cortical cells, triggering intracellular signaling cascades that promote the synthesis and release of glucocorticoids (e.g., cortisol). This action also modulates adrenal growth, lipid metabolism, and immune responses, making it a key tool for studying HPA axis dynamics, adrenal steroidogenesis, and stress – induced physiological changes.

2.PRODUCT INDICATIONS

ACTH (1-14) is indicated for research applications in endocrinology (e.g., adrenal insufficiency studies), neuroendocrinology (stress – related disorder modeling), and pharmaceutical R & D (developing ACTH – based therapeutics for inflammatory or autoimmune conditions). It is also valuable for preclinical studies exploring glucocorticoid regulation, adrenal development, and metabolic homeostasis.

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3.CLINICAL EFFICACY OF PRODUCT

In research settings, ACTH (1-14) has demonstrated consistent efficacy in stimulating glucocorticoid secretion, validating its role in HPA axis research. Its high purity and stability support reproducible experiments, enabling accurate assessment of adrenal function, stress responses, and therapeutic potential of ACTH – related interventions. For preclinical models of adrenal disorders, it helps evaluate treatment strategies targeting glucocorticoid dysregulation.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: ACTH (1-14), Peptide, Adrenal Hormone, Endocrine Research, Glucocorticoid, Stress Response, HPA Axis, Pharmaceutical Intermediate, Preclinical Research, High Purity Peptide

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510