β-Amyloid (10-20) CAS NO.152286-31-2

β-Amyloid (10-20) is a synthetic peptide fragment widely utilized in neurological research to investigate the molecular mechanisms underlying Alzheimer's disease and amyloid aggregation. This high-purity peptide serves as a critical tool for scientists exploring the structural dynamics of beta-amyloid peptides and their role in neurodegeneration. Its well-defined sequence and consistent quality make it ideal for in vitro and in vivo experimental models aimed at understanding disease progression and evaluating potential therapeutic interventions. Researchers value this compound for its reliability in generating reproducible data across various biochemical and biophysical assays.

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	β-Amyloid (10-20)
CAS NO.	152286-31-2
Appearance	White to off-white lyophilized powder
Molecular Formula	C71H99N17O16
Molecular Weight	~1446.68 g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in water, DMSO; insoluble in ethanol, acetone, chloroform
Endotoxin	≤10 EU/mg
Biological Activity	Forms amyloid fibrils; used for studying Alzheimer's disease pathology and Aβ aggregation mechanism
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

β-Amyloid (10-20) functions as a model peptide that recapitulates key structural and biochemical properties of full-length β-amyloid aggregates, facilitating studies on fibrillogenesis, neurotoxicity, and membrane disruption. Upon administration in experimental systems, it readily forms insoluble amyloid fibrils that mimic pathological deposits observed in Alzheimer’s brains, enabling researchers to probe the early events of aggregation and the interaction of oligomeric species with neuronal receptors. The peptide’s ability to induce cellular stress responses and synaptic dysfunction provides insights into the pathogenic cascade triggered by amyloidogenic proteins, supporting mechanistic investigations into neurodegeneration.

2.PRODUCT INDICATIONS

This peptide is specifically indicated for use in academic and industrial research focused on Alzheimer’s disease, Parkinson’s disease, and other amyloid-related neurodegenerative disorders. It is suitable for applications in molecular biology, neurochemistry, and drug discovery, including the development of aggregation inhibitors, diagnostic probes, and neuroprotective agents. Researchers in both basic science and translational medicine utilize this fragment to model disease phenotypes, screen compound libraries, and validate biomarkers associated with amyloid pathology. Its compatibility with cell culture, animal models, and spectroscopic techniques makes it indispensable for multidisciplinary neuroscience studies.

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3.CLINICAL EFFICACY OF PRODUCT

While β-Amyloid (10-20) is not intended for human clinical use, its efficacy is demonstrated in preclinical research settings where it consistently reproduces amyloidogenic behavior and neurotoxic effects observed in human brain tissue. Studies using this peptide have contributed to the validation of novel therapeutic targets and the optimization of imaging agents for early detection of amyloid plaques. Its reliable fibrillation kinetics and dose-dependent toxicity profiles support its use as a benchmark standard in evaluating the efficacy of anti-amyloid compounds, thereby accelerating the development of potential disease-modifying therapies for Alzheimer’s and related dementias.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: β-Amyloid, Alzheimer's Disease, Peptide, Neurodegeneration, Amyloid Aggregation, Research Chemical, Neurotoxicity, Dementia, Beta-Amyloid Fragment, Preclinical Research, Molecular Biology, Neurochemistry, Drug Discovery, Therapeutic Target, Biomarker, Fibrillogenesis, Neuroprotection, Scientific Research, High Purity, Lab Reagent

If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510