MetLysBradykinin CAS 550196 Factory and Reliable Suppliers in China
Met-Lys-Bradykinin (CAS NO.550-19-6) is a high-purity bradykinin analog and potent B2 receptor agonist designed for advanced biomedical research. By specifically interacting with the B2 subtype of bradykinin receptors, this peptide triggers essential intracellular signaling cascades, making it an indispensable tool for studying vasodilation, inflammatory responses, and vascular permeability in preclinical pharmacological models.
Engineered for stability and precision, Met-Lys-Bradykinin serves as a critical pharmacological probe for evaluating receptor binding affinity and selectivity. It is widely utilized in GPCR signaling research, calcium flux assays, and drug discovery pipelines aimed at modulating the kallikrein-kinin system for the treatment of cardiovascular and inflammatory disorders.
Detailed Parameters
| Product Name | Met-Lys-Bradykinin | CAS NO. | 550-19-6 |
|---|---|---|---|
| Molecular Formula | C61H94N18O13S | Molecular Weight | 1319.61 g/mol |
| Purity (RP-HPLC) | ≥99.0% | Appearance | White to off-white powder |
| Solubility | Water, dilute acetic acid | Endotoxin | ≤1.0 EU/mg |
| Storage | -20°C, dry, dark container | Stock Location | USA |
Key Advantages
Ultra-High Purity
Guaranteed ≥99.0% purity via RP-HPLC, ensuring consistent and reproducible results in sensitive receptor assays.
Enhanced Stability
Unique N-terminal structure provides improved metabolic stability against peptidases compared to native Bradykinin.
Precise Agonism
Specifically targets B2 receptors to stimulate nitric oxide synthesis and smooth muscle relaxation.
Validated Activity
Proven efficacy in inducing vascular permeability and prostaglandin synthesis in endothelial cells.
Low Endotoxin
Maintained at ≤1.0 EU/mg, minimizing non-specific cellular responses in in vitro research.
Full Traceability
Each batch includes COA, MS chromatograms, and HPLC reports for total quality transparency.
Product Gallery
Management Platforms
GMP Production
Strict adherence to GMP-compliant systems for synthesis and purification processes.
QC Validation
Standardized quality control covering raw materials to final packaging.
Cold Chain Logic
Specialized -20°C storage and shipping to maintain peptide biological activity.
Global Logistics
Fast international air freight via DHL, FedEx, and UPS for rapid delivery.
Scale Flexibility
Capabilities ranging from gram-level research samples to ton-level industrial supply.
Regulatory Compliance
Compliant with international trade standards and pharmaceutical API regulations.
Investment Return Comparison
| Metric | Standard Grade | GlobalTech Premium Grade |
|---|---|---|
| Purity Level | ≥95.0% | ≥99.0% (HPLC Verified) |
| Metabolic Stability | Low / Native | High / Modified N-terminal |
| Endotoxin Control | Not Specified | Strictly ≤1.0 EU/mg |
| Documentation | Basic COA | Full COA, MS, and HPLC Reports |
| Delivery Speed | Standard Shipping | Express USA-based Stocking |
Frequently Asked Questions
It is primarily used for in vitro laboratory research, receptor binding assays, and preclinical studies on the kininergic system, specifically targeting the B2 receptor to study inflammation and vasodilation.
Met-Lys-Bradykinin features a modified N-terminal structure that enhances its metabolic stability and alters its interaction with enzymes like ACE, providing a more reliable probe for research.
The product should be stored at -20°C in a dry, dark, and well-sealed container. It is crucial to avoid repeated freeze-thaw cycles to preserve biological activity.
No. Met-Lys-Bradykinin is strictly designated for in vitro laboratory research and preclinical pharmacological studies; it is not a clinical therapeutic agent.
Every batch comes with a comprehensive Certificate of Analysis (COA), RP-HPLC purity reports, and mass spectrometry (MS) chromatograms to verify identity and purity.
We use professional secure packaging with temperature-controlled solutions and fast international air freight (DHL/FedEx/UPS) to minimize environmental exposure.
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