Defensin HNP-2 (human), identified by CAS NO. 120721-97-3, is a high-potency antimicrobial peptide essential for bridging innate and adaptive immunity. By interacting with anionic microbial membranes, it creates transmembrane pores that lead to bacterial depolarization and lysis, while simultaneously acting as a powerful chemoattractant for monocytes and T lymphocytes.
Engineered for precision research, this product is an indispensable tool for scientists investigating innate immunity, antimicrobial resistance, and inflammatory disorders. Whether utilized in in vitro assays, cell culture studies, or animal models, our HNP-2 provides the high purity and biological activity required to develop next-generation therapeutic strategies against infectious diseases.
| Product Name | Defensin HNP-2 (human) | CAS NO. | 120721-97-3 |
|---|---|---|---|
| Appearance | White to off-white lyophilized powder | Molecular Formula | C₁₄₇H₂₁₇N₄₃O₃₇S₆ |
| Molecular Weight | 3370.95 g/mol | Purity (RP-HPLC) | ≥99.0% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water | Endotoxin | < 1 EU/mg |
| Storage Conditions | Store at -20°C, protected from light and moisture | Stock Location | Stock in USA |
RP-HPLC purity ≥99.0% ensures consistent experimental results and eliminates interference from impurities.
Demonstrated broad-spectrum antimicrobial activity and precise immune cell chemoattraction.
Produced via GMP-compliant systems with strict quality control from raw materials to packaging.
Each batch includes COA, HPLC reports, and MS chromatograms for complete traceability.
Endotoxin levels < 1 EU/mg, making it safe for sensitive cell culture and in vivo studies.
Specialized cold-chain packaging and express air freight via DHL/FedEx for global stability.
Rigorous quality management systems ensuring batch-to-batch consistency and stability.
Standardized synthesis and purification processes adhering to international pharmaceutical standards.
Professional laboratory testing including mass spectrometry and HPLC validation for every lot.
Strict adherence to international trade standards and pharmaceutical regulatory guidelines.
Flexible supply capabilities ranging from milligram scale for research to ton-level for industry.
Advanced cold-chain shipping and secure packaging to maintain peptide integrity worldwide.
| Evaluation Metric | Standard Grade Peptides | GlobalTech Research Grade |
|---|---|---|
| Purity Levels | 95% - 98% | ≥99.0% (HPLC) |
| Endotoxin Control | Not Specified | < 1 EU/mg |
| Documentation | Basic COA | COA + HPLC + MS Reports |
| Stability Data | Limited | Comprehensive Batch Traceability |
| Delivery Speed | Standard Shipping | Priority Air Freight (DHL/FedEx) |
HNP-2 is primarily used in studying innate immunity, developing new antimicrobial agents to combat resistance, and researching inflammatory modulations in infectious disease models.
It should be stored as a lyophilized powder at -20°C. It is critical to protect the product from light and moisture to prevent degradation.
Yes, HNP-2 is soluble in 1M acetic acid, DMSO, or deionized water, depending on your specific assay requirements.
Our production partners operate under GMP-compliant systems and many possess DMF and FDA certifications to ensure global pharmaceutical standards.
Yes, while we provide internal HPLC and MS reports, third-party testing reports are available upon request to ensure absolute transparency.
We utilize international air freight via DHL, FedEx, UPS, and TNT, which typically ensures the fastest transit times and real-time tracking for all global shipments.