7Acetyltaxol CAS 92950395 China Suppliers and Factory Price
7-Acetyltaxol (CAS NO. 92950-39-5) is a high-purity semi-synthetic taxane derivative designed for advanced biomedical research. As a potent microtubule stabilizer and mitotic inhibitor, it serves as a critical tool in oncological studies, mimicking the biological activity of paclitaxel by binding to the beta-tubulin subunit to prevent chromosomal segregation and trigger apoptosis in rapidly dividing cells.
Primarily utilized as a certified reference material, 7-Acetyltaxol is indispensable for pharmaceutical developers and analytical chemists. It is widely employed in HPLC and Mass Spectrometry (MS) to establish impurity profiles and ensure the quality of paclitaxel APIs, providing a reliable benchmark for quantifying related substances and evaluating the cytotoxic potential of novel taxane structural optimizations.
Detailed Parameters
| Product Name | 7-Acetyltaxol | CAS NO. | 92950-39-5 |
|---|---|---|---|
| Molecular Formula | C49H53NO15 | Molecular Weight | 895.94 g/mol |
| Purity (RP-HPLC) | ≥98% | Appearance | White to off-white amorphous powder |
| Solubility | Soluble in DMSO, Chloroform, Ethyl Acetate | Endotoxin | ≤ 5 EU/mg |
| Storage | Store at -20°C, protected from light | MOQ | 1g |
Key Advantages
Ultra-High Purity
Certified ≥98% purity via RP-HPLC, ensuring precise and reproducible results for sensitive analytical research.
Rapid US Delivery
Strategically stocked in USA warehouses to minimize transit times and ensure rapid project turnaround.
GMP Compliance
Produced by partners utilizing GMP-compliant systems with standardized quality control across all stages.
Full Traceability
Complete documentation provided, including COA, HPLC purity reports, and MS chromatograms for every batch.
Bio-Active Standard
Demonstrated IC50 values around 60 nM, serving as a gold standard for microtubule dynamics benchmarking.
Custom Packaging
Professional vacuum-sealed, light-protected packaging tailored to maintain stability during global transit.
Product Gallery
Management Platforms
Raw Material Control
Strict procurement protocols ensuring only pharmaceutical-grade precursors enter the synthesis chain.
Synthesis Precision
Advanced semi-synthetic processes to maintain structural integrity at the C-7 hydroxyl modification site.
Quality Validation
Multi-stage testing using High-Performance Liquid Chromatography and Mass Spectrometry.
Cold Chain Logistics
Specialized -20°C shipping environment to prevent degradation of heat-sensitive taxanes.
Batch Traceability
Unique batch numbering system linking every gram to its specific synthesis and testing record.
Regulatory Support
Provision of DMF and FDA-compliant documentation to support international trade and research.
Investment Return Comparison
| Feature | Standard Grade | GlobalTech Premium |
|---|---|---|
| Purity Level | ≥95% | ≥98% (Certified) |
| Documentation | Basic COA | COA + HPLC + MS Report |
| Delivery Speed | 14-21 Days | 3-5 Days (US Stock) |
| Stability | Variable | High (Strict -20°C Control) |
| Technical Support | Limited | Professional Analytical Support |
Frequently Asked Questions
It is primarily used as a certified reference standard for the identification and quantification of impurities in Paclitaxel APIs, helping manufacturers maintain strict quality control via HPLC and MS.
While it is an acetylated derivative at the C-7 position, preclinical data shows it retains core cytotoxic potential and the ability to promote microtubule assembly similar to Paclitaxel.
To ensure stability and prevent degradation, 7-Acetyltaxol must be stored at -20°C in a tightly sealed container, protected from both moisture and direct light.
No, this product is strictly indicated for non-clinical, in vitro research applications and laboratory analysis only.
7-Acetyltaxol is highly soluble in DMSO, Chloroform, and Ethyl Acetate, but it is insoluble in water.
We employ a rigorous quality management system utilizing GMP-compliant production and third-party validation, providing full HPLC and MS chromatograms for every batch.
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