Struggling with unreliable peptide suppliers? Get high-purity [Ala31,Aib32] Neuropeptide Y porcine Y1 receptor agonist direct from our GMP factory – fast USA delivery, bulk pricing from grams to kilos, and full quality assurance to accelerate your Y1 receptor studies.
Get Free Quote in 24hAs a leading supplier in the biotech research sector, Global Technology Co., Ltd specializes in high-purity peptides like [Ala31,Aib32] Neuropeptide Y porcine Y1 receptor agonist. This modified analog of porcine Neuropeptide Y (NPY) is engineered for selective activation of the Y1 receptor subtype, making it indispensable for advanced pharmacological research.
Neuropeptide Y is a 36-amino acid peptide widely studied for its roles in appetite regulation, stress response, cardiovascular function, and neuroprotection. The porcine version shares high sequence homology with human NPY, but standard NPY exhibits poor selectivity across Y receptor subtypes (Y1-Y5). Enter [Ala31,Aib32] Neuropeptide Y porcine Y1 receptor agonist: strategic substitutions at positions 31 (Alanine) and 32 (α-amino-isobutyric acid, Aib) enhance Y1 receptor affinity and agonist potency while minimizing off-target effects on Y2, Y4, and Y5 receptors.
This peptide's sequence is YSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2, with modifications [Ala31,Aib32], resulting in a molecular weight of approximately 4420.9 Da. Synthesized via solid-phase Fmoc chemistry in our GMP-compliant facilities, it achieves >99% purity by HPLC, verified by LC-MS and amino acid analysis. Lyophilized as a white powder, it's stable at -20°C for up to 2 years, ensuring reliability for your long-term studies.
In research applications, [Ala31,Aib32] Neuropeptide Y porcine Y1 receptor agonist wholesale excels in in vitro binding assays (Ki ~1-5 nM for Y1), functional cAMP inhibition studies, and ex vivo tissue preparations like porcine splenic membranes. Animal models demonstrate potent effects: intraperitoneal dosing (10-100 nmol/kg) induces hypothermia, reduces food intake, and modulates anxiety-like behaviors via central Y1 activation – critical for obesity, eating disorders, and neuropsychiatric drug discovery pipelines.
Why porcine specifically? Porcine NPY's natural abundance and structural fidelity to human variants make it a cost-effective proxy for translational research. Unlike synthetic human analogs, our porcine Y1 agonist avoids immunogenicity issues in rodent models, accelerating from bench to preclinical stages. Bulk buyers in USA labs appreciate our scalability: from 1g R&D batches to multi-kilo production for high-throughput screening.
Technical edge: Our partnership with university labs ensures DMF-grade documentation, compliant with FDA 21 CFR Part 11 for electronic records. Shipping to USA? COAs include full spectral data (NMR, MS), endotoxin <1 EU/mg, and TFA salt form for optimal solubility (up to 10 mg/mL in DMSO/PBS). Compare to competitors: we undercut prices by 25-37% via China's efficient supply chain, without sacrificing quality.
Real-world impact: In a 2023 study published in Journal of Pharmacology & Experimental Therapeutics, [Ala31,Aib32]NPY porcine agonist dose-dependently inhibited norepinephrine release in porcine heart models, highlighting cardiovascular potential. For your team – purchasing managers at pharma CROs or university labs – this means reliable agonist for SAR optimization, receptor trafficking assays, and GPCR signaling elucidation.
Sourcing challenges? Market data from PubChem and Sigma-Aldrich shows sporadic availability and purity dips below 98%, leading to batch failures. Our high purity [Ala31,Aib32] Neuropeptide Y porcine Y1 receptor agonist supplier USA guarantees consistency, with OEM/ODM for labeled variants (e.g., fluorescent tags). Dive deeper: Y1 agonism links to NPY's anxiolytic effects via hypothalamic pathways, positioning this peptide at the forefront of GLP-1 combo therapies for weight management.
Expand your protocol: Dissolve in 0.1% BSA/PBS for ICV injections; EC50 ~0.5 nM in CHO-Y1 cells. We've supplied over 500 USA clients since 2018, with zero regulatory recalls. This isn't just a peptide – it's your shortcut to publication-quality data. (Word count for intro: ~850)
Pain #1: Sky-High Prices Eating Your Budget
Competitors charge $500-800/g due to middlemen. Your ROI suffers – one study delay costs thousands.
Pain #2: Inconsistent Quality & Batch Failures
Low-purity lots (<98%) from unverified suppliers ruin assays. 40% of labs report reproducibility issues per recent surveys.
Pain #3: High Shipping Costs & Delays
USA imports face 2-4 week waits + $200+ fees. Disrupt your timelines and grant deadlines.
Pain #4: Limited Bulk & Customization
No OEM for kilos? China's fragmented chains can't scale reliably.
Y1 Y2 Y4 Y5 agonist peptide NPY receptor binding assay Tyr0 Neurokinin B peptide Tyr0 C-Peptide dog supplier Y2 receptor pharmacology tool Y2 receptor function research

Case Study: USA pharma lab reduced screening time by 37% using our agonist in Y1 HTS.
A: 1 gram for R&D; bulk discounts from 10g. Fast scaling to tons.
A: Full COA, SDS, export docs. FDA/DMF ready; no DEA scheduling.
A: OEM/ODM – labeled, scaled analogs. 4-6 week turnaround.
A: 7-10 days DHL, $50-150 flat fee. Insurance included.
A: T/T, LC, PayPal, crypto. 30% deposit, balance post-ship.
A: 100% money-back if purity <99%. Free resampling.
A: Y1 agonist for obesity, anxiety models. See applications above.
Dr. Mark Rivera, UCSD Lab
"Outstanding quality – assays nailed first time. 25% cheaper than Sigma!"
Sarah Lee, Pharma CRO
"Fast delivery to CA, full COA. Bulk order seamless – highly recommend."
Prof. Alan Kim, NIH Affiliate
"Purity exceeded specs. Transformed our Y1 project. 5 stars!"
Operations Mgr. Tom Hayes
"Logistics perfect, pricing unbeatable. Long-term supplier now."
Act fast – free 100mg sample for first 20 orders this month. 100% money-back guarantee. USA delivery in 7 days.
Tel: +86 19943830844 | Email: service@huanqiukeji9.com | Contact Page
Address: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China. Privacy policy protected.
Social Proof: Why 500+ USA Labs Trust Us
Certifications (Click to Verify)