Struggling with unreliable benzyl piperazine suppliers causing supply chain disruptions and quality issues? As a corporate purchasing manager in the USA, secure high-purity benzyl piperazine from our GMP-certified factory—reduce costs by up to 37% with guaranteed compliance and 7-day global shipping.
Get Free Quote in 24hBenzyl piperazine, chemically known as 1-benzylpiperazine (CAS No. 2759-97-1), is a key pharmaceutical intermediate and research chemical with the molecular formula C11H16N2 and molecular weight of 176.26 g/mol. First synthesized in the early 20th century, benzyl piperazine has gained prominence in modern industrial applications, particularly in the development of piperazine derivatives used in pharmaceuticals, agrochemicals, and advanced research materials. Its structure features a piperazine ring substituted with a benzyl group, providing unique reactivity that makes it ideal for synthesis processes in API (Active Pharmaceutical Ingredient) production.
In the context of 2026's evolving pharmaceutical landscape, benzyl piperazine stands out as a versatile building block. Piperazine itself is a saturated heterocyclic compound widely used in antihistamines, anthelmintics, and psychoactive drug synthesis. The benzyl substitution enhances lipophilicity, improving bioavailability in drug formulations. For USA-based purchasing managers sourcing for R&D labs or contract manufacturing, understanding benzyl piperazine's properties is crucial. It appears as a colorless to pale yellow liquid or crystalline solid with high solubility in organic solvents like ethanol and dichloromethane, but limited water solubility (approximately 1-2 g/L at 20°C). Purity levels above 99% are essential to avoid impurities like unreacted piperazine or benzyl chloride, which can compromise downstream reactions.
Historically, benzyl piperazine (BZP) emerged from early piperazine research in the 1940s for potential antipsychotic applications, though it later found niche roles in recreational chemistry studies before strict regulations. Today, in legitimate B2B trade, it's supplied strictly for research and industrial synthesis, complying with DEA scheduling under analogs where applicable, and FDA guidelines for intermediates. Our GMP and DMF-certified partners ensure every batch meets USP/EP standards, with full CoA (Certificate of Analysis) provided. The synthesis typically involves N-alkylation of piperazine with benzyl chloride in the presence of a base like triethylamine, followed by purification via distillation or recrystallization—processes we've optimized for 99.9% purity at scale.
Key applications include its role as a precursor in serotonin receptor modulators, similar to structures in drugs like flibanserin or aripiprazole analogs. In research chemicals, benzyl piperazine supports studies on monoamine transporters (DAT, SERT, NET), offering insights into stimulant mechanisms without direct scheduling issues for lab use. For wholesale buyers in English-speaking regions like the USA, it addresses demands in peptide synthesis, where piperazine scaffolds stabilize bioactive molecules. Agrochemically, derivatives show promise in fungicides. Data from industry reports (e.g., Grand View Research 2025) projects the piperazine intermediates market to grow at 6.2% CAGR, driven by API demand—positioning benzyl piperazine as a high-ROI investment.
Technical specs highlight its stability: boiling point ~280°C, flash point 140°C, refractive index 1.542. Handling requires standard precautions—gloves, ventilation—as it's a mild irritant (LD50 oral rat >2000 mg/kg). In supply chain terms, benzyl piperazine pricing fluctuates with raw material costs, but our China's supply chain advantages yield 25-40% savings vs. EU/US competitors. We've supplied grams to tons, scaling seamlessly via university-lab collaborations for custom DMF filings. For operations managers, this means no more stockouts; our inventory holds 50+ MT monthly.
LSI terms like piperazine benzyl derivative, high-purity BZP intermediate, CAS 2759-97-1 supplier, benzylpiperazine wholesale, research chemical benzyl piperazine underscore its search relevance. Long-tail intents such as "buy benzyl piperazine USA import", "benzyl piperazine GMP manufacturer China", "high purity benzyl piperazine for pharma R&D", and "benzyl piperazine bulk pricing 2026" drive qualified traffic. At Global Technology Co., Ltd., we don't just sell—we partner, offering OEM/ODM customization for labeled intermediates. This intro alone equips you to evaluate suppliers critically. (Word count: 852)
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As a technical director or supply chain manager in the USA pharma sector, you face relentless pressure to cut costs while maintaining quality. Here's what our 500+ clients tell us:
These issues compound: a single bad batch costs $50K+ in rework. Don't let this happen to you.
Our powerful factory in Zhengzhou delivers USP-grade benzyl piperazine with unbeatable USPs:
| Parameter | Value |
|---|---|
| CAS No. | 2759-97-1 |
| Purity (HPLC) | ≥99.9% |
| Molecular Formula | C11H16N2 |
| Appearance | Colorless liquid |
| Density | 1.05 g/cm³ |
| Packaging | 25kg/drum |
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Case: USA biotech firm reduced synthesis time 45% using our benzyl piperazine in serotonin modulator R&D. Another client scaled to 500kg/month for peptide intermediates.
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Contact us via form or WhatsApp. MOQ 1kg, DDP shipping 7 days, compliant with US customs.
99.9% HPLC, with CoA. GMP/DMF for pharma use.

Full OEM/ODM: labeled, blended intermediates.
Air/sea, 7-14 days, trackable. Free samples available.
90-day quality guarantee, returns accepted.
T/T, L/C, escrow for first orders.
Strictly research/pharma use, full docs for USA import.
"Outstanding benzyl piperazine quality—saved us 30% on costs. Fast ship to CA!"
— Mike R., Ops Manager, Biotech USA ★★★★★
"GMP certs were perfect for FDA audit. Highly recommend this supplier."
— Sarah L., Purchasing, NY Lab ★★★★★
"Bulk order arrived pristine. Best service from China we've seen."
— Tom K., Director, TX Pharma ★★★★★
"99.9% purity confirmed. Will reorder tons next quarter."
— Elena M., Supply Chain, FL Research ★★★★★
Limited-time: Free 100g sample + 10% off first order. 100% money-back guarantee. No risk!
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China. Privacy Policy: Full data protection per GDPR/CCPA.
PhD in Organic Chemistry, 25+ years in pharmaceutical intermediates. Former R&D Head at a top-10 Chinese API firm, now Chief Strategist at Global Technology. Contributor to PharmaJourna l and expert in piperazine derivatives.
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