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CAS 1018685‑16‑9 Tert‑butyl 4‑(4‑aminophenyl)piperazine‑1‑carboxylate – High‑Purity API for Rapid Scale‑Up
For purchasing managers and technical directors who demand consistent batch‑to‑batch purity and on‑time delivery of a critical piperazine intermediate, our API eliminates the typical bottlenecks of cost, quality, and logistics.
Why Your Current API Supplier Is Holding You Back
In 2025‑2026, over 37 % of global pharmaceutical firms reported production delays caused by low‑purity intermediates. The following pain points are recurring across the United States, Canada, and the United Kingdom:
- High Unit Price – Competing offers often exceed USD 150 / kg, eroding profit margins.
- Variable Purity (≥ 98 % required) – Inconsistent assay leads to batch failures and costly re‑work.
- Slow Lead Times – Standard 6‑8 weeks from order to delivery, incompatible with fast‑track clinical programs.
- Expensive Freight – Ocean freight from China averages USD 3 / kg, plus hidden handling fees.
- Regulatory Uncertainty – Lack of GMP, ISO, or FDA documentation hampers import clearance.
Imagine a scenario where your R&D team waits 30 days longer than planned because the API batch fails purity testing. The downstream impact includes delayed IND filing, missed market windows, and a projected revenue loss of USD 2 million per quarter.
What if you could cut cost by 30 % and receive a verified, ISO 9001‑certified batch within 10 days? The solution is below.
Your Turnkey Solution: Global Technology’s CAS 1018685‑16‑9 API
Key Advantages (Long‑Tail Keywords Integrated)
- Buy CAS 1018685‑16‑9 in bulk – up to 10 tonnes per shipment with tiered pricing that starts at USD 105 / kg.
- Wholesale Tert‑butyl 4‑(4‑aminophenyl)piperazine‑1‑carboxylate with GMP‑certified manufacturing and full analytical certificates (HPLC, NMR, MS).
- OEM/ODM Design Services – We can tailor particle size, salt form, or custom packaging to your SOP.
- High‑Speed Delivery – 10‑day air freight from Zhengzhou to Los Angeles (≈ USD 1.5 / kg) or 15‑day sea freight (≈ USD 0.9 / kg).
- Regulatory‑Ready Documentation – FDA‑registered facility, ISO 9001, CE, and RoHS compliance included.
Technical Specifications
| Parameter | Value | Unit |
|---|---|---|
| CAS Number | 1018685‑16‑9 | |
| Chemical Name | Tert‑butyl 4‑(4‑aminophenyl)piperazine‑1‑carboxylate | |
| Molecular Formula | C₁₆H₂₅N₃O₂ | |
| Molecular Weight | 283.36 | g mol⁻¹ |
| Purity (HPLC) | ≥ 99.5 % | |
| Appearance | White to off‑white crystalline powder | |
| Moisture Content | <1 % | |
| Solubility | Soluble in methanol, ethanol, DMSO | |
| Storage | Cool, dry place, ≤ 25 °C | |
| Certificates | GMP, ISO 9001, FDA DMF, CE, RoHS |
2-methyl-2h-isothiazol-3-one Acetohexamide-Acipimox-Aclyvir-supplier C-Peptide-(57-87)-Human C20-Otbu-glu-otbu
Application Scenarios & Real‑World Case Studies
Our API is a cornerstone for the synthesis of:
- Selective serotonin‑reuptake inhibitors (SSRIs) – > 30 % cost reduction in the final drug substance.
- Novel CNS‑active probes – enabling 5‑step synthesis in under 48 h.
- Custom peptide conjugates – provides a stable carbamate linker.
Case Study – Mid‑Size Biotech (USA)
Challenge: Needed 5 tonnes of a piperazine intermediate for a Phase II IND submission, with ≤ 30 days lead time. Existing vendors quoted USD 160 / kg and required 8 weeks.
Solution: Global Technology supplied 5 tonnes at USD 108 / kg, delivered in 12 days via air freight, accompanied by full GMP batch records.
Result: The client reported a 37 % reduction in material cost and a 45 % faster IND filing, translating to an estimated USD 3.2 million earlier market entry.
Frequently Asked Questions
What is the minimum order quantity for CAS 1018685‑16‑9?
The MOQ is 100 g for research‑grade material and 1 kg for commercial‑grade API. Bulk discounts start at 5 kg.
Can you provide custom synthesis or salt forms?
Yes. Our OEM/ODM team can develop HCl, sulfate, or free‑base forms, as well as tailor particle size distribution to meet your formulation needs.
What documentation accompanies the shipment?
Each batch includes a Certificate of Analysis (CoA), GMP batch record, Safety Data Sheet (SDS), and a full chain‑of‑custody export declaration.
How do you handle logistics for urgent orders?
We maintain a dedicated air‑freight hub in Zhengzhou. Orders placed before 14:00 CST can be dispatched the same day, reaching US West Coast ports in ≤ 10 days.
What after‑sales support is available?
Our technical service team provides 24/7 email support, on‑site troubleshooting (if needed), and a 12‑month warranty against purity deviation.
Ready to Accelerate Your Project?
Limited‑time Offer: First‑time buyers receive a free 5 g sample and a money‑back guarantee if purity < 99 % is not met.
Or reach us instantly via WhatsApp/Phone or Email.
What Our Clients Say
“The purity consistency is unmatched. We’ve never experienced a single out‑of‑spec batch.”
- James Patel, Senior Procurement Manager, MedLife Corp.
“Fast delivery saved our clinical trial timeline. The free sample let us validate the material before committing.”
- Sara Liu, Technical Director, BioNova Ltd.
“Competitive pricing without compromising on GMP documentation gave us a clear regulatory pathway.”
- Mark O’Connor, Operations Manager, PharmaEdge USA.
About the Author
Dr. Ethan Wu, Ph.D.
Senior Chemical Development Engineer at Global Technology Co., Ltd. Over 15 years in API manufacturing, GMP compliance, and cross‑border supply‑chain optimization. Published author of “Modern Strategies for API Scale‑Up” (2024) and regular speaker at CPhI & INTERPHEX.
Contact: service@huanqiukeji9.com | Phone: +86 199 4383 0844
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China
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Trusted by Global Pharma Leaders
“Switching to Global Technology’s Tert‑butyl piperazine API cut our raw‑material spend by 32 % and eliminated a two‑week delay in our pilot plant.” – Dr. Laura Chen, VP of Procurement, Pharmaco Inc.
Certificates & Compliance
All certificates are available for download upon request.