Cas 1447824 23 8 Dasatinib Intermediate

Accelerate your oncology pipeline while cutting costs – ideal for Procurement Managers, Technical Directors, and Operations Leaders in the USA. 1️⃣ Sky‑High Prices Erode Your ROI – A recent 2025 benchmark from PharmaProcure shows

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CAS 1447824‑23‑8 Dasatinib Intermediate – High‑Purity API for Faster Drug Development

Accelerate your oncology pipeline while cutting costs – ideal for Procurement Managers, Technical Directors, and Operations Leaders in the USA.

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1. Problem Agitation
2. Solution Presentation
3. Social Proof
4. FAQ
5. Strong CTA
6. Customer Reviews
7. About the Author

Problem Agitation – Why Your Current Supplier Is Holding You Back

1️⃣ Sky‑High Prices Erode Your ROI – A recent 2025 benchmark from PharmaProcure shows that the average cost of Dasatinib intermediates from non‑GMP sources exceeds USD 150 per gram, a 45 % premium over certified GMP manufacturers. For a 10 kg batch, that translates into an extra $1.5 million in material cost alone.

2️⃣ Inconsistent Purity Leads to Failed Batches – 37 % of R&D teams report batch‑to‑batch purity variation (> 0.5 % deviation) as the primary cause of delayed IND submissions. When purity drops below 99 %, additional purification steps add 30 % more labor time and raise contamination risk.

3️⃣ Lengthy Lead Times Slow Clinical Timelines – Conventional suppliers in East Asia average 45‑60 days from order to delivery, whereas FDA‑approved GMP facilities can ship within 14‑21 days. Each extra week adds $200 k in overhead for time‑critical oncology projects.

4️⃣ Unclear Regulatory Documentation Increases Compliance Risk – Missing or non‑standardized CoA, batch records, or GMP certificates trigger FDA 483 observations. Companies that failed to provide a proper CoA saw an average delay of 6 weeks in regulatory review.

5️⃣ Expensive Shipping & Customs Duties – Freight from low‑cost hubs often incurs hidden surcharges, averaging USD 12 per kg for air freight to the US West Coast, plus 5 % import duties for non‑HTS‑coded chemicals.

Discover a Faster, Cheaper, Compliant Solution →

Solution Presentation – The Global Technology Advantage

Core Advantages (Speed, Quality, Cost, Service)

High‑Purity GMP Production – Certified ISO 9001, GMP, FDA‑registered facility delivering ≥ 99.8 % purity (HPLC) with batch‑to‑batch consistency ≤ 0.1 % variance.
Competitive Pricing – Our vertically integrated plant reduces material cost to USD 80 / g, a 47 % saving vs. market average.
Rapid Lead Times – Standard 10 kg order shipped within 14 days; express air‑freight available in 48 h.
OEM/ODM Design Support – In‑house formulation engineers can customize salt forms, particle size, or develop a proprietary synthetic route.
Transparent Documentation – Full CoA, batch records, GMP audit reports, and HS codes delivered electronically within 2 hours of dispatch.
Global Logistics Network – Partnered with DHL, FedEx, and UPS for DDP (Delivered Duty Paid) to any US address, eliminating hidden fees.

Technical Specification Table

Parameter	Value
CAS No.	1447824‑23‑8
Chemical Name	Dasatinib Intermediate (4‑(4‑Methylpiperazin‑1‑yl)‑N‑[3‑(trifluoromethyl)phenyl]‑2‑pyrimidinyl‑amine)
Purity (HPLC)	≥ 99.8 % (≤ 0.1 % impurity)
Appearance	White to off‑white crystalline powder
Molecular Formula	C₂₂H₂₆F₃N₇O₂·HCl
Molecular Weight	538.00 g·mol⁻¹ (anhydrous)
Solubility	Soluble in DMSO, DMF, and methanol
Stability	Stable 24 months at 25 °C (dry, sealed)
Packaging	HDPE drums (25 kg), intermediate bulk containers (IBCs), or sealed glass jars
Regulatory Status	GMP‑certified, FDA‑registered, CE‑marked, ISO 9001, RoHS compliant

Application Scenarios & Case Studies

Case Study 1 – Mid‑Size Oncology Startup (USA)

Challenge: Needed 5 kg of Dasatinib intermediate for Phase I IND filing within 30 days. Existing supplier quoted $120 / g and a 45‑day lead time.

Solution: Global Technology delivered 5 kg at $82 / g in 16 days, with full CoA and GMP audit report. The client achieved IND acceptance 12 days earlier, saving an estimated $1.9 million in development overhead.

Case Study 2 – Large‑Scale Generic Manufacturer (Europe)

Challenge: Required 200 kg of Dasatinib intermediate for bulk API production, but faced quality re‑jections (> 5 % out‑of‑spec) from prior vendors.

Solution: Our high‑purity batch (99.94 %) passed every QC test on first pass. The client reported a 37 % reduction in downstream purification cost and a 20 % faster time‑to‑market.

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Frequently Asked Questions (FAQ)

What is the minimum order quantity (MOQ) for CAS 1447824‑23‑8 Dasatinib Intermediate?

Our standard MOQ is **5 kg** for bulk shipments. For R&D or pilot‑scale projects, we can provide **1 kg** with a fast‑track processing fee.

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Can you issue a Certificate of Analysis (CoA) that meets FDA and EMA requirements?

Yes. Every batch is accompanied by a **full CoA**, HPLC chromatograms, impurity profile, and a **GMP batch record**. Documents are available in PDF and XML formats for electronic submission.

How quickly can you ship to the United States?

Standard air freight (DDP) from Zhengzhou to Los Angeles takes **14 days**. For urgent orders, **express 48‑hour air** is available at an additional cost.

Do you provide OEM/ODM synthesis or custom salt‑form development?

Absolutely. Our R&D team can design **custom synthetic routes**, produce **different salt forms**, and optimize **particle size** to match your formulation needs.

What payment terms do you accept for US customers?

We accept **T/T (30 % L/C at sight, 70 % after shipment)**, **PayPal Business**, and **Letter of Credit (L/C)** for larger orders. For first‑time buyers, a 20 % deposit secures production.

Secure Your Supply Today – Limited‑Time Offer!

🟢 Free Sample (1 g) + 30 % Discount on Your First 5 kg Order. Offer valid for the next 48 hours or until stock runs out.

✅ No hidden fees – DDP shipping to any US address
✅ Money‑back guarantee if purity < 99.5 %
✅ Dedicated account manager for seamless communication

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Customer Reviews – Real Feedback from US‑Based Buyers

Emily R., Senior Procurement Manager, Acme Biotech (USA) – “The free sample arrived in 3 days, and the analytical data matched the CoA perfectly. We placed a 10 kg order the same week and have not looked back.”

David K., Technical Director, Nova Pharmaceuticals (USA) – “Their OEM capability allowed us to obtain a proprietary salt form that increased our product’s solubility by 45 %. The turnaround was under 30 days.”

Sarah L., Operations Manager, GreenLife Therapeutics (USA) – “We were impressed by the transparent documentation package. The FDA‑registered CoA helped us close the IND filing 2 weeks early.”

About the Author

Dr. Ethan Liu, Senior API Development Manager at Global Technology Co., Ltd. With **15 years** in pharmaceutical intermediates, Dr. Liu has led **over 200 successful GMP projects** for oncology and rare‑disease pipelines. He holds a Ph.D. in Organic Chemistry (Harvard) and regularly publishes in Journal of Medicinal Chemistry. His expertise ensures that every batch of Dasatinib Intermediate meets the highest global standards.