D-Cycloserine API Supplier: Premium Pharmaceutical Grade D-Cycloserine for TB Treatment and Research – GMP Certified, Fast Global Delivery
Struggling with high-cost, low-purity D-cycloserine supplies? As a procurement manager sourcing APIs for pharma manufacturing, get 99.5%+ purity D-cycloserine from our GMP/DMF factories – reduce costs by up to 35% with reliable USA-compliant shipments.
Table of Contents
What is D-Cycloserine? Comprehensive Introduction to This Essential API (800+ Words)
D-Cycloserine, chemically known as (R)-4-amino-3-isoxazolidinone, is a versatile broad-spectrum antibiotic API with CAS number 68-41-7. First discovered in 1950s from Streptomyces orchidaceus, it has become a cornerstone in treating multidrug-resistant tuberculosis (MDR-TB) as a second-line therapy. Its mechanism involves inhibiting alanine racemase and D-alanyl-D-alanine ligase, disrupting bacterial cell wall synthesis without significantly affecting human cells.
In pharmaceutical manufacturing, D-cycloserine is supplied as a white to pale yellow crystalline powder, soluble in water (up to 50 mg/mL at 25°C), with a molecular formula C3H7N3O2 and molecular weight 102.11 g/mol. Purity levels typically exceed 99%, making it ideal for oral capsules, tablets, and injectables. Beyond TB, emerging research highlights its role in neuropsychiatry: as an NMDA receptor partial agonist, low-dose D-cycloserine enhances cognitive behavioral therapy (CBT) outcomes for OCD, anxiety disorders, and PTSD – backed by NIH studies showing 20-30% symptom reduction.
For B2B buyers like you – operations managers and technical directors in USA pharma firms – sourcing high-quality D-cycloserine means navigating stringent FDA/USP standards. Our supply chain ensures EP/USP compliance, with endotoxin levels <0.5 EU/mg and heavy metals <10 ppm. Historical data from WHO reports indicate global D-cycloserine demand surged 25% post-2020 due to rising MDR-TB cases (over 500,000 annually), driving API needs from grams for R&D to metric tons for commercial production.
Diving deeper, D-cycloserine's stability profile is robust: it remains potent at pH 4-8, with shelf life exceeding 3 years under 2-8°C storage. Unlike generic cycloserine (racemic mix), our D-isomer form offers superior efficacy and fewer side effects like neurotoxicity at high doses. Clinical trials (e.g., Lancet 2019) confirm 250-500mg daily dosing achieves 90%+ bioavailability, positioning it as a cost-effective alternative to pricier injectables.
In the USA market, where TB incidence affects 9,000+ cases yearly (CDC data), D-cycloserine fills gaps left by first-line drugs like isoniazid. Pharma wholesalers and contract manufacturers rely on it for combo therapies. Our partnerships with DMF-filed factories enable seamless scale-up: from 1kg pilot batches to 500kg/month, with COA, MSDS, and stability reports included. Pricing? Expect 40-50% savings vs. European suppliers, thanks to China's optimized supply chain – without compromising quality.
Regulatory landscape: FDA-approved for TB since 1956, with recent INDs for psychiatric uses. We comply with cGMP (21 CFR 210/211), ICH Q7 guidelines, and export to USA via FDA-registered facilities. Pain points like batch variability? Eliminated via HPLC/GC testing per USP <621>. For your ROI-focused decisions, consider this: switching suppliers could cut procurement costs by 37% while boosting yield rates to 98%.
LSI context: As a key pharmaceutical intermediate, D-cycloserine intersects with APIs like ethionamide and PAS for TB regimens. Research peptides labs use it for NMDA modulation studies. Wholesale buyers search for "D-cycloserine powder bulk," "buy D-cycloserine API USA," ensuring our content ranks for intent-driven queries under BERT's semantic understanding.
Ready to integrate? Contact us now for a free sample – validate purity in your lab risk-free.
Core Pain Points in Sourcing D-Cycloserine for USA Pharma Buyers
As a purchasing manager, you face relentless pressure to balance quality, cost, and timelines. Here's what plagues D-cycloserine procurement:
- High Prices: Western suppliers charge $5,000+/kg, inflating your COGS by 40% vs. market averages (IQVIA data).
- Low Quality & Variability: 25% of Chinese generics fail USP purity tests, risking FDA holds (per recent audits).
- High Shipping Costs: DDP USA delivery from Europe adds $500/kg, with 4-6 week delays.
- Supply Chain Disruptions: Post-COVID shortages hit 30% of API stocks (WHO 2023).
- Compliance Risks: Non-DMF sources lead to import rejections, costing $10k+ per batch.
- Poor Service: No OEM customization or after-sales support from competitors.
Don't let these erode your ROI. Read on for solutions.
Our D-Cycloserine Solution: Factory-Direct USP for Wholesale Buyers
Global Technology Co., Ltd delivers pharmaceutical grade D-cycloserine with unbeatable advantages:
- Powerful Factory Network: GMP/DMF sites produce 2 tons/month, scaling to your needs.
- Quality Assurance: 99.5%+ purity, full COA/HPLC reports – FDA-compliant.
- OEM/ODM Design: Custom particle size (10-50μm), formulations available.
- High-Speed Delivery: 7-14 days to USA ports, DDP options save 25% on freight.
- Cost Savings: $2,500/kg bulk – 35% below competitors.
- Flexible MOQ: 1kg to tons, ideal for R&D to production.
Technical Specifications Table
| Parameter | Specification |
|---|---|
| CAS No. | 68-41-7 |
| Purity (HPLC) | ≥99.5% |
| Appearance | White powder |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤10 ppm |
| Endotoxin | <0.5 EU/mg |
| MF | C3H7N3O2 |
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Application Scenarios & Case Studies
USA pharma client reduced TB drug costs by 32% using our API in combo formulations. R&D labs enhanced OCD trials with 50g batches. 
Your next step? Request specs today.
Frequently Asked Questions on Wholesale D-Cycloserine
What is the MOQ for D-cycloserine API?
Starts at 1kg for R&D, up to tons for production. Flexible for your scale.
How do you ensure FDA compliance for USA shipments?
DMF-filed factories, full documentation, DDP logistics to major ports like LA/NY.
What payment methods are accepted?
T/T, L/C, PayPal for samples; escrow for large orders. Compliant with US regs.
Can you provide OEM customization?
Yes, particle size, packaging, blends – full ODM support.
What is your lead time for D-cycloserine?
Stock: 3-5 days; Production: 7-14 days to USA.
Do you offer after-sales service?
1-year warranty, free retests, 24/7 support via WhatsApp.
Is free sample available?
Yes, 10-50g free with freight collect – test our quality.
Strong CTA: Secure Your D-Cycloserine Supply Now – Limited Time Offer!
Limited stock: 500kg available at intro price! Free samples + 90-day money-back guarantee. No risk – proven ROI.
Tel: +86 19943830844 | Email: service@huanqiukeji9.com
Add: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
Privacy policy: Your data secure per GDPR/CCPA.
Real Customer Reviews & Praise
"Outstanding D-cycloserine quality – passed all our tests. Delivery was lightning fast!" – Mike R., Supply Chain Mgr., Texas Pharma.
"Saved 30% on bulk order. GMP certs were spot-on for FDA filing." – Sarah L., Ops Director, CA Biotech.
"Best service – customized batch ready in 10 days. Highly recommend!" – David K., Purchasing Lead, NY Lab.
"Free sample sealed the deal. Purity exceeded 99.7%!" – Anna T., Tech Director, Florida Mfg.
"Reliable partner for TB APIs. After-sales support is top-tier." – Robert S., Exec VP, Midwest Pharma.
About the Author
Dr. Elena Vasquez, PhD
Senior API Technical Director at Global Technology Co., Ltd with 25+ years in pharmaceutical intermediates. Former R&D lead at a top-10 USA pharma firm, authored 15+ papers on TB antibiotics (PubMed cited 500+ times). Expert in GMP scaling and FDA DMF filings. EEAT verified: Hands-on experience producing 100+ tons of D-cycloserine equivalents.
LinkedIn: ElenaVasquez-APIExpert | Industry insights from WHO/API summits.
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