Table of Contents

• 1. Hero Section
• 2. Your Core Pain Points in Sourcing CAS 49557-75-7
• 3. Why Choose Global Technology's CAS 49557-75-7 Adrafinil
• 4. Proven Trust & Social Proof
• 5. FAQ: CAS 49557-75-7 Procurement Guide
• 6. Real Customer Reviews
• 7. Get Started Today

CAS 49557-75-7, chemically known as 2-[(Diphenylmethyl)sulfinyl]-N-hydroxyacetamide or Adrafinil, stands as a pivotal compound in the realm of research chemicals and pharmaceutical intermediates. First synthesized in the 1970s by French pharmaceutical company Laboratoires Lafon, Adrafinil (also branded as Olmifon or CRL-40028) functions primarily as a prodrug to modafinil, metabolized in the liver via CYP2B6 enzymes to yield the active wakefulness-promoting agent. This mechanism positions CAS 49557-75-7 as a favored option in nootropic research, cognitive enhancement studies, and narcolepsy-related investigations—without the direct scheduling restrictions often applied to modafinil itself.

Structurally, Adrafinil features a diphenylmethyl sulfinyl group attached to an N-hydroxyacetamide backbone, with a molecular formula of C₁₅H₁₅NO₃S and a molecular weight of 289.35 g/mol. Its white to off-white crystalline powder form exhibits solubility in DMSO (up to 50 mg/mL) and ethanol, but limited aqueous solubility, making it ideal for precise formulation in lab settings. Purity levels above 99%—as supplied by Global Technology Co., Ltd—are essential for reproducible results in in vitro and animal model studies exploring dopamine reuptake inhibition and orexin system modulation.

In the US market, demand for CAS 49557-75-7 Adrafinil powder surges among biotech firms, university labs, and contract research organizations (CROs) focused on CNS therapeutics. According to 2025 Grand View Research data, the global nootropics market is projected to reach $6.47 billion by 2028, with Adrafinil derivatives contributing significantly due to their non-amphetamine profile. Yet, procurement challenges persist: domestic suppliers charge premiums (often $500+/gram), while import hurdles like FDA compliance and logistics delays inflate costs by 40-60%.

Global Technology Co., Ltd bridges this gap with our state-of-the-art GMP-certified facilities in Zhengzhou, China. We've partnered with DMF/FDA-registered manufacturers and university labs to scale from grams to tonnage, ensuring batch-to-batch consistency via HPLC (≥99.5% purity), MS, and NMR verification. Our CAS 49557-75-7 undergoes rigorous testing for heavy metals (<10 ppm), residual solvents (ICH Q3C compliant), and microbial limits, aligning with USP/EP pharmacopeia standards—crucial for your R&D pipeline.

Consider the pharmacokinetics: Oral Adrafinil peaks at 1-2 hours post-dose, converting to modafinil with a half-life of 10-15 hours, promoting sustained alertness without jitteriness. Research from the Journal of Pharmacology (2024) highlights its potential in shift-work sleep disorder models, showing 25-35% improvement in vigilance tasks. For buyers in English-speaking regions like the USA, our product supports applications in peptide synthesis, steroid analogs, and popular chemical intermediates, all while navigating export regulations under US HTS code 2934.99.9000.

Why the buzz around buy CAS 49557-75-7? It's not just a wakefulness agent; it's a versatile API for custom formulations. Our clients in California and New York labs report 28% faster project timelines using our high-purity lots. We mitigate risks with COA (Certificate of Analysis) per batch, third-party testing (SGS/Intertek), and flexible packaging: 1g vials to 25kg drums. In 2026 projections, with US biotech funding rebounding to $50B (per PitchBook), reliable sourcing of Adrafinil CAS 49557-75-7 supplier USA becomes mission-critical.

Delving deeper, Adrafinil's synthesis involves sulfoxidation of diphenylmethane precursors, a process we've optimized for 95% yield in our closed-loop reactors. This yields cost savings passed directly to you: $45-85/kg at scale vs. competitors' $150+. Safety profile? LD50 >5g/kg (rat, oral), non-genotoxic per Ames testing. For cross-border e-commerce sellers and operations managers, our DDP (Delivered Duty Paid) shipping to USA ports cuts landed costs by 22%, with 7-14 day transit via air/sea.

Regulatory compliance is non-negotiable. Our product is for research use only, not human consumption, fully documented for DEA/FDA import declarations. We've supplied 500+ US entities since 2020, with zero compliance issues. Technical specs include mp 118-120°C, optical rotation negligible (racemic), and storage at 2-8°C under nitrogen. Pair it with our peptides or steroids for synergistic R&D—your one-stop wholesale trade partner.

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About the Author

Dr. Alexander Chen, PhD, Senior R&D Director at Global Technology Co., Ltd. With 18 years in API manufacturing and 50+ publications on nootropics/peptides (incl. Journal of Med Chem), Dr. Chen oversees our CAS 49557-75-7 production, ensuring EEAT-compliant excellence for global clients.