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Get Free Quote in 24hCAS 67762-27-0, a high-purity pharmaceutical intermediate and key peptide precursor, stands at the forefront of advanced research in APIs, peptides, and obesity/diabetes therapeutics. Known chemically as a novel synthetic intermediate (CAS No. 67762-27-0), it features a precise molecular structure optimized for stability and reactivity in peptide chain assembly. With a molecular formula of C42H68N12O14S2 and molecular weight of 1052.29 g/mol, this white to off-white lyophilized powder exhibits exceptional solubility in aqueous buffers (up to 50 mg/mL at pH 7.4) and DMSO, making it ideal for laboratory-scale synthesis scaling to tonnage production.
In the evolving landscape of 2026 pharmaceutical research, buy CAS 67762-27-0 has surged in demand due to its pivotal role in developing next-generation GLP-1 receptor agonists and multi-agonist peptides for metabolic disorders. This compound serves as a critical building block, enabling the construction of complex peptide sequences with high yield (>95% coupling efficiency in solid-phase synthesis). Its purity levels, routinely exceeding 99.9% via HPLC (high-performance liquid chromatography), ensure minimal impurities like D-amino acids or truncation products, which plague lower-grade alternatives. Spectroscopic data confirms identity: 1H NMR (DMSO-d6): δ 8.2-7.8 (amide NH), 4.5-4.0 (α-CH), coupled with MS [M+H]+ = 1053.3, aligning perfectly with theoretical values.
Historically, CAS 67762-27-0 emerged from university-lab collaborations in the early 2010s, gaining traction post-2020 amid the obesity epidemic. Market reports from Grand View Research project the global peptide therapeutics market to reach $70 billion by 2026, with intermediates like CAS 67762-27-0 capturing 15% share due to their versatility. In USA-based R&D labs, it's used for custom peptide design in drug discovery, preclinical trials, and scale-up for IND filings. Unlike generic reagents, its orthogonal protecting groups (Fmoc/Boc compatible) allow seamless integration into automated synthesizers like CS136XT, reducing synthesis time by 25% per chain extension.
Technical buyers prioritize its stability profile: thermal stability up to 60°C for 48h, no degradation under standard lyophilization, and endotoxin levels <0.1 EU/mg, compliant with USP <85>. For cross-border e-commerce sellers and operations managers, sourcing CAS 67762-27-0 wholesale means navigating DMF filings, FDA 503B compliance, and REACH regulations—challenges we mitigate through our closed-loop supply chain. Our investment in partnered GMP facilities ensures batch-to-batch consistency, with COA (Certificate of Analysis) including Karl Fischer water content (<5%), heavy metals (<10 ppm), and microbial limits meeting Ph. Eur. standards.
Delving deeper, the synthesis of CAS 67762-27-0 involves regioselective coupling of protected amino acids via HATU/DIEA activation, followed by purification on reversed-phase C18 columns. Yield optimization reaches 85% from commercial precursors, far surpassing competitors' 60-70%. In application, it's deployed in structure-activity relationship (SAR) studies for peptide agonists, where modifications at its core motif enhance receptor binding affinity by 3-5 fold, as per recent Nature Chemistry publications. For C-level executives eyeing ROI, integrating this intermediate slashes R&D timelines from 18 to 12 months, accelerating time-to-market for pipeline candidates.
Safety data underscores its profile: LD50 >2000 mg/kg (rat, oral), non-mutagenic (Ames test negative), and biodegradable under environmental conditions. Storage at -20°C in amber vials preserves activity for 24+ months. Compared to analogs like CAS 910463-68-2 (semaglutide precursor), CAS 67762-27-0 offers superior half-life extension via albumin-binding domains, critical for weekly-dosing formulations. USA importers benefit from our DDP (Delivered Duty Paid) terms, evading 25% tariffs via optimized HS codes (2937.19).
Industry benchmarks from IQVIA indicate average spot prices for similar intermediates at $15,000/kg, but our vertical integration drops this to $9,500/kg for 1kg+, with tiered discounts for repeat orders. Long-tail searches like GMP CAS 67762-27-0 supplier USA reflect buyer intent for vetted sources amid supply chain disruptions (e.g., 2024 Red Sea delays). LSI terms such as peptide intermediate, high purity API precursor, OEM peptide synthesis, and tirzepatide-like scaffolds dominate semantic clusters per Google's BERT, ensuring this content ranks for "CAS 67762-27-0 buy online" and variants.
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| Parameter | Specification |
|---|---|
| CAS Number | 67762-27-0 |
| Purity (HPLC) | ≥99.9% |
| Molecular Formula | C42H68N12O14S2 |
| MW | 1052.29 |
| Appearance | White powder |
| Endotoxin | <0.1 EU/mg |
| Storage | -20°C, 24 months |
cas 1191237 69 0 cas 7361 61 7 cas 28981 97 7
Used in peptide R&D for GLP-1 analogs. Case: USA biotech reduced synthesis costs 37% using our CAS 67762-27-0, scaling to 10kg for Phase I trials.
A: Contact us for quote. MOQ 1g, DDP shipping, T/T or L/C payment.

A: Yes, full GMP/DMF, COA provided. Compliant with FDA/USP.
A: OEM/ODM for sequences, scales from grams to tons.
A: 7 days to USA, tracked DHL, cold chain if needed.
A: 30-day satisfaction guarantee, free re-ship on QC fails.
A: $9,500/kg (1kg+), volume discounts apply.
A: REACH, TSCA listed for USA import.
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