Buy CAS 100111-07-7 Wholesale | 99.5% Purity Pharmaceutical Intermediate from GMP-Certified Factory

Struggling with unreliable suppliers for high-purity CAS 100111-07-7? As a purchasing manager in pharma R&D or manufacturing, you need consistent quality, fast delivery to USA, and competitive pricing to meet ROI targets. Get 99.5% pure CAS 100111-07-7 with full DMF/FDA compliance—direct from our powerful factory.

CAS 100111-07-7, chemically known as 4-(4-Bromophenyl)piperidin-4-ol, is a critical pharmaceutical intermediate widely used in the synthesis of advanced APIs and research chemicals. With the formula C₁₁H₁₄BrNO and molecular weight of 256.14 g/mol, this compound features a piperidine ring substituted with a 4-bromophenyl group at the 4-position, along with a hydroxyl group, making it highly versatile for medicinal chemistry applications.

In 2026, as pharmaceutical R&D accelerates in English-speaking regions like the USA, demand for high-purity CAS 100111-07-7 has surged by 45% year-over-year, according to industry reports from IQVIA and Statista. This growth is driven by its role as a key building block in developing novel therapeutics, including antipsychotics, analgesics, and anti-inflammatory drugs. Sourcing reliable CAS 100111-07-7 suppliers remains a top challenge for operations managers, with supply chain disruptions causing delays in 32% of projects (Deloitte Pharma Survey 2025).

Our deep dive into CAS 100111-07-7 reveals its physical properties: white to off-white crystalline powder, melting point 178-182°C, solubility in DMSO >100 mg/mL, and stability under standard storage (2-8°C, protected from light). These attributes ensure it's ideal for scalable synthesis. Global Technology Co., Ltd leverages GMP-certified facilities to produce it at 99.5% purity, exceeding USP/EP standards.

Historically, CAS 100111-07-7 entered commercial prominence in the early 2000s as an intermediate for fentanyl analogs and other piperidine-based opioids, though today it's primarily used in legitimate pharma R&D. Regulatory compliance is paramount—our product holds DMF filings with the US FDA, ensuring seamless integration into your ANDA/NDA filings. Compared to competitors relying on fragmented China's supply chains, we offer end-to-end traceability via blockchain-enabled COA.

Technically, the synthesis of CAS 100111-07-7 involves Grignard reaction of 4-bromophenylmagnesium bromide with 4-piperidone, followed by hydrolysis. We optimize this with proprietary catalysis, achieving 92% yield and reducing impurities to <0.1%. For USA buyers, this means lower COGS—our bulk pricing starts at $150/kg for 100kg+, a 37% savings vs. European suppliers.

Safety profile: LD50 >2000 mg/kg (rat, oral), non-mutagenic per Ames test. Handling requires standard PPE; our SDS complies with GHS and OSHA. In applications, it's pivotal for SAR studies in CNS disorders, where piperidine scaffolds modulate receptor affinity. Recent publications in Journal of Medicinal Chemistry (2025) highlight its derivatives achieving 85% efficacy in preclinical models.

Market dynamics in 2026 show buy CAS 100111-07-7 searches spiking 60% on Google Trends, fueled by post-pandemic R&D investments ($250B globally). Yet, pain points persist: inconsistent quality (45% rejection rate), high MOQ from small vendors, and shipping delays averaging 21 days. Global Technology bridges this with high-speed delivery (7-14 days to USA via DHL/FedEx) and flexible grams-to-tonne scaling.

Quality assurance at our Zhengzhou facility includes HPLC (99.5% purity), GC-MS for residuals, and ICH Q3D elemental impurities testing. We partner with university labs for custom analytics. For OEM/ODM, we tailor particle size (D90 <10μm) or isotopic labeling. This positions us as the go-to CAS 100111-07-7 supplier USA.

Environmental footprint: Our green synthesis cuts solvent use by 40%, aligning with REACH and TSCA. Cost-benefit analysis shows switching to us yields 30% ROI in 90 days via reduced waste and faster time-to-market. Ready to secure your supply? Request a sample today.

Your Core Pain Points Sourcing CAS 100111-07-7

As a technical director or supply chain manager, you face relentless pressure to deliver high-ROI projects. Here's how unreliable CAS 100111-07-7 suppliers derail your goals:

• High Prices Eating Margins: Competitors charge $250+/kg due to middlemen—your budget balloons 40% without volume discounts.
• Low Quality Causing Rejections: 35% of batches fail purity tests (HPLC <98%), triggering FDA holds and $50K rework costs per incident (PharmaTech Report 2025).
• High Shipping Costs & Delays: 21-day ocean freight from China adds $15/kg + tariffs; stockouts halt production lines for weeks.
• Regulatory Compliance Gaps: Missing DMF/COA leads to audit failures; 28% of USA imports rejected at customs (CBP data).
• Limited Customization: No OEM/ODM options force redesigns, delaying launches by 6 months.
• Unreliable Scalability: Grams OK, but tonnes? Fragmented supply chains collapse under demand.

Scenario: Your Q1 trial run fails purity specs—project slips to Q3, costing $200K. Sound familiar? Discover how we fix this. Scroll to solutions →

Our CAS 100111-07-7 Solution: Powerful Factory Advantages

Global Technology Co., Ltd delivers CAS 100111-07-7 with unmatched USPs, solving your pains head-on.

• Powerful Factory Capacity: 5-tonne/month output from 10,000m² GMP site—scale from grams to tonnes seamlessly.
• Quality Assurance: 99.5% purity, full DMF/FDA, batch-to-batch consistency <0.2% variance.
• OEM/ODM Design: Custom synthesis, chiral resolution, or analogs—your specs, our execution.
• High-Speed Delivery: 7-14 days to USA door, DDP terms, $8/kg air freight.
• Cost Leadership: $150/kg bulk—37% below market.
• Full Compliance: REACH, TSCA, export-ready with COA/SDS.

Technical Specifications Table

cas 1191237 69 0 cas 10597 60 1 cas 225779-44-2

Application Scenarios & Case Studies

Used in CNS drug synthesis: e.g., 80% yield in fentanyl derivative trials. Case: USA pharma firm scaled 500kg order—reduced costs 32%, launched API in 45 days.

Next Step: Schedule a demo to see our process.

Social Proof: Why 500+ Clients Trust Us

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Testimonials

"Switched to Global Tech for CAS 100111-07-7—purity hit 99.7%, delivery in 9 days. Saved 28% on costs."
— Dr. Emily R., Technical Director, USA Pharma Corp

"Full DMF compliance streamlined our FDA filing. OEM batch was perfect."
— Mike T., Supply Chain Manager, Bay Area Labs

Certifications

• GMP
• DMF/FDA
• ISO 9001
• REACH/TSCA

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FAQ: Buy CAS 100111-07-7 Wholesale

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Real Customer Reviews

"Outstanding quality on CAS 100111-07-7. Delivery beat expectations, pricing unbeatable. Highly recommend for USA buyers."

— Sarah L., Ops Manager, Texas

"GMP certs and fast response made procurement seamless. 99.6% purity confirmed in-house."

— Robert K., Purchasing Dir., California

"From quote to delivery: 10 days. Saved us 35% vs. previous supplier. Top service!"

— Lisa M., Supply Chain Lead, New York

"Custom ODM batch was flawless. True partner for pharma intermediates."

— James P., R&D Head, Florida

About the Author

Dr. Alexander Chen, PhD

Senior VP of R&D at Global Technology Co., Ltd. With 25+ years in pharmaceutical intermediates, Dr. Chen holds a PhD in Organic Chemistry from Tsinghua University and has authored 40+ papers on piperidine derivatives. He oversees our CAS 100111-07-7 production, ensuring EEAT-compliant excellence. Experience from Pfizer collaborations informs every insight here.

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