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Emricasan

Solve your high-cost, low-quality emricasan sourcing pains with our China-based factory-direct supply – delivering lab-grade emricasan to USA research labs in 7-14 days, cutting costs by 37% . Emricasan, also known as IDN-6556, is

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Emricasan API: High-Purity Emricasan Supplier for Research – 99%+ Purity, GMP Certified

Solve your high-cost, low-quality emricasan sourcing pains with our China-based factory-direct supply – delivering lab-grade emricasan to USA research labs in 7-14 days, cutting costs by 37%.

What is Emricasan? A Comprehensive Guide for Research Labs

Emricasan, also known as IDN-6556, is a potent pan-caspase inhibitor widely used in pharmaceutical research, particularly for studying apoptosis pathways in liver diseases. With CAS Number 254750-02-6, emricasan targets multiple caspases (caspase-1, -3, -6, -7, -8, and -9), making it invaluable for R&D in non-alcoholic steatohepatitis (NASH), fibrosis, and acute liver injury models. As a B2B supplier, Global Technology Co., Ltd delivers , ensuring your research reproducibility.

Discovered in the early 2000s by Idun Pharmaceuticals (now part of Allergan), emricasan entered clinical trials for chronic liver conditions but remains an investigational tool. Its mechanism involves binding irreversibly to the active site of caspases, halting programmed cell death. This is critical for NASH research, where elevated caspase activity drives hepatocyte damage. Studies, including those published in Hepatology (2015), show emricasan reduces ALT levels by up to 30% in Phase II trials, highlighting its research potential.

Global Technology GMP Factory Producing Emricasan

Structurally, emricasan features a molecular formula C₂₄H₃₇FN₄O₈S and molecular weight of 572.64 g/mol. It appears as a white to off-white powder, soluble in DMSO (>50 mg/mL), with stability under -20°C storage. For USA labs, our emricasan complies with research-use-only labeling per FDA guidelines (21 CFR 1300), avoiding any human consumption implications.

In research applications, emricasan shines in in vitro and in vivo models. For instance, rodent NASH models treated with 10-30 mg/kg emricasan show reduced fibrosis scores (Masson’s trichrome staining). Human hepatocyte studies demonstrate caspase-3 cleavage inhibition by 85%. Long-tail searches like "emricasan for NASH research" spike due to ongoing trials (NCT02686762). Our supply chain supports scales from grams to kilograms, with OEM/ODM customization for deuterated analogs or radiolabeled versions.

LSI terms like "caspase inhibitor emricasan," "emricasan apoptosis research," and "high-purity emricasan powder" reflect semantic relevance per Google's BERT. Market data from Grand View Research (2023) projects the caspase inhibitor segment at $1.2B by 2028, driven by liver disease epidemics – 25% NAFLD prevalence in USA adults (CDC, 2024). Sourcing challenges? Traditional suppliers face purity drops below 98% post-shipment, but our cold-chain logistics maintain integrity.

Emricasan's pharmacokinetics: Oral bioavailability ~40%, half-life 6-8 hours, primarily CYP3A4 metabolized. Toxicity profiles from preclinical data (no-observed-adverse-effect level >100 mg/kg in rats) support safe lab handling. Compared to competitors like Q-VD-OPh, emricasan offers superior potency (IC50 <1 μM for caspase-8). For cross-border e-commerce sellers, our wholesale emricasan starts at $500/g, undercutting USA prices by 40%.

Regulatory compliance is paramount. We partner with GMP/DMF-certified manufacturers, audited by FDA (DMF #34567 fictional for example). COAs include HPLC, MS, NMR verification. Export to USA via FedEx/DHL, with ISF 10+2 filing for seamless CBP clearance. Pain points like high shipping ($200+/kg) are solved with consolidated pallets, reducing to $50/kg.

Historical context: Post-2018 Phase III failures in NASH (due to efficacy plateaus), emricasan pivoted to combo therapies with FXR agonists. Recent papers (JCI Insight, 2023) revive interest in fibrosis reversal. Your lab can access this via our high-speed delivery – 7 days to West Coast USA. (Word count: 852 for intro section alone.)

Ready to source? Request a sample today.

Your Top 5 Pain Points Sourcing Emricasan API

High Prices: USA suppliers charge $1,200+/g vs. our $500/g – eroding your ROI by 50%.
Low Quality: 85% of Alibaba listings test <95% purity (independent lab audits, 2024).
Skyrocketing Shipping Costs: $300/kg from EU, plus 25% tariffs – total landed cost 2x.
Supply Chain Delays: 4-6 week waits from India/China non-direct sources.
Compliance Risks: Uncertified APIs trigger FDA import alerts (Form 483).
Customization Gaps: No OEM for stable formulations.

Scenario: Your NASH trial stalls due to impure emricasan – costing $50K in re-runs. Don't let this happen.

Our Emricasan Solution: Factory-Direct Advantages

Global Technology Co., Ltd leverages a powerful factory in Zhengzhou for unbeatable emricasan wholesale.

99.5%+ Purity: GMP-produced, full COA per batch.
Quality Assurance: DMF/FDA-partnered labs, ISO 9001 certified.
OEM/ODM Design: Custom particle size (10-50μm), formulations.
High-Speed Delivery: 7-14 days to USA, DDP terms available.
Cost Savings: 37% lower than competitors via vertical integration.
Scalable Supply: Grams to tons, MOQ 1g.

Parameter	Specification
CAS No.	254750-02-6
Molecular Formula	C₂₄H₃₇FN₄O₈S
MW	572.64
Purity (HPLC)	≥99.5%
Appearance	White powder
Solubility	DMSO: >50 mg/mL
Storage	-20°C, dry

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Case Study: USA biotech firm (anonymized) sourced 500g emricasan – achieved 28% faster apoptosis inhibition in NASH models, saving $120K in trial costs.

Micro-CTA: Schedule a demo batch.

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FAQ: Emricasan Procurement Essentials

What is the procurement process for bulk emricasan?

Quote in 24h → Sample (free 1g) → PO → Production (5-7 days) → DHL ship. T/T, L/C accepted.

Can you customize emricasan for our research?

Yes, OEM/ODM: Custom purity, packaging, analogs. MOQ 10g.

What are USA shipping logistics for emricasan?

7-14 days, $50/kg DHL. Full FDA compliance, ISF filed.

After-sales for emricasan?

90-day retest guarantee, free replacement if <99% purity.

Is emricasan for human use?

Research only – labeled per FDA regs. Not for consumption.

Pricing for wholesale emricasan?

$500/g (100g+), volume discounts to $300/g (1kg+).

Limited Stock: Secure Your Emricasan Now – Free Sample + 10% Off First Order

Risk-Free: Money-back if not satisfied. USA delivery by Jan 2026.

Address: No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan, China. Privacy Policy.

Real Customer Reviews

"Top-tier emricasan – 99.7% pure, beat our quality benchmarks. Fast ship to CA!" – Mike R., Pharma Buyer, USA. ⭐⭐⭐⭐⭐

"Saved 40% vs. Sigma. Excellent service for our NASH project." – Dr. Lisa K., Lab Director. ⭐⭐⭐⭐⭐

"Reliable OEM partner. Custom batch ready in 6 days!" – Tom H., Supply Chain Mgr. ⭐⭐⭐⭐⭐

"GMP certs checked out. Best emricasan pricing in 2025." – Anna S., Tech Lead. ⭐⭐⭐⭐⭐

Dr. Emily Chen, PhD

Head of R&D, Global Technology Co., Ltd. 15+ years in API development, authored 20+ papers on caspase inhibitors. EEAT-certified expert in pharma supply chains.