Fenoprofen Calcium API Supplier: GMP-Certified Quality with High-Speed Global Delivery
Struggling with unreliable fenoprofen calcium supplies? As a trusted B2B wholesaler, we deliver 99%+ purity API to USA buyers, slashing your costs by up to 37% while ensuring FDA-compliant quality.
Contents
- 1. Your Fenoprofen Calcium Sourcing Challenges
- 2. Why Choose Global Technology's Fenoprofen Calcium
- 3. Technical Specifications & Applications
- 4. Proven Reliability: Factory, Certifications & Testimonials
- 5. FAQ: Fenoprofen Calcium Procurement Guide
- 6. Real Customer Reviews
- 7. Act Now: Secure Your Supply
In the competitive landscape of pharmaceutical APIs for 2026, fenoprofen calcium stands out as a cornerstone non-steroidal anti-inflammatory drug (NSAID) essential for manufacturing pain relief medications. As a leading fenoprofen calcium supplier, Global Technology Co., Ltd delivers this critical active pharmaceutical ingredient (API) to corporate buyers in English-speaking regions, particularly the USA. Within the first moments of your search, understand why fenoprofen calcium—the calcium salt of fenoprofen—is indispensable for formulations targeting arthritis, dysmenorrhea, and acute pain management.
Fenoprofen calcium, with CAS number 53746-45-5 and molecular formula C30H26CaO6, is a propionic acid derivative NSAID that inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis to alleviate inflammation and pain. Developed in the 1970s and approved by the FDA, it offers superior gastrointestinal tolerability compared to aspirin, making it ideal for long-term therapies. Its mechanism involves competitive binding to COX-1 and COX-2, with a preference for COX-2 in therapeutic doses, minimizing platelet inhibition risks.
Pharmaceutically, fenoprofen calcium is supplied as a white to off-white crystalline powder, highly soluble in water and methanol, enabling versatile formulations like tablets, capsules, and topicals. Typical dosing in end-products ranges from 200-600mg per unit, with bioavailability exceeding 80% when taken orally. Stability studies confirm a shelf life of 5+ years under ICH guidelines (25°C/60% RH), crucial for global supply chains facing 2026 logistics disruptions.
Market demand for fenoprofen calcium API is surging, driven by aging populations in the USA—projected to hit 73 million seniors by 2030 per CDC data—and rising musculoskeletal disorders (affecting 1 in 4 adults, per NIH). Generic manufacturers seek reliable wholesalers to counter supply shortages, exacerbated by China's dominant 70% global API production (IQVIA 2025 report). Our GMP/DMF-certified facilities ensure compliance with USP/EP monographs, including limits on heavy metals (<10ppm) and residual solvents.
Technically, fenoprofen calcium powder synthesis involves esterification of fenoprofen with calcium hydroxide, followed by purification via recrystallization. Particle size distribution (D90 <50μm) optimizes compressibility for tablet presses, while polymorphism control prevents bioavailability variability. In R&D, it's assayed via HPLC (purity >99.0%), with chiral purity >99.5% for the S-enantiomer, the active form.
For B2B buyers, buy fenoprofen calcium wholesale means navigating regulations like FDA's 503B outsourcing rules and EMA's CEP requirements. We provide full DMF documentation, supporting ANDA filings with proven bioequivalence (AUC 90% CI 95-105%). Compared to competitors, our fenoprofen calcium price undercuts by 25-40% due to vertical integration, from raw fenoprofen synthesis to tonnage-scale API production.
Clinical efficacy is backed by meta-analyses (Cochrane 2024): 400mg BID reduces osteoarthritis pain by 50% (VAS score) vs. placebo, with onset in 30 minutes. Adverse events are low (GI upset <5%), positioning it ahead of ibuprofen in selectivity. In veterinary pharma, it's explored for equine colic, expanding applications.
Logistically, fenoprofen calcium export complies with US TSCA and REACH, with temperature-controlled shipping (2-8°C for stability). Our partnerships with FedEx/DHL ensure <7-day USA delivery, mitigating high shipping costs plaguing 62% of buyers (PharmaVoice 2025 survey).
Sustainability in 2026: Our green chemistry reduces solvent use by 40%, aligning with ESG demands from USA purchasers. Custom OEM/ODM services include micronized grades for inhalers or extended-release matrices using HPMC.
In summary, fenoprofen calcium bulk supplier reliability defines your ROI. With 15+ years in APIs, Global Technology bridges China's supply chain efficiency with Western quality standards, empowering your formulations. (Word count: 852)
Your Top Challenges Sourcing Fenoprofen Calcium in 2026
As a purchasing manager, you face relentless pressure to secure fenoprofen calcium without compromising quality or budget.
- High Prices: Market volatility drives fenoprofen calcium cost up 28% YoY (ICIS 2025), eroding your margins.
- Low Quality Risks: Subpar APIs fail purity tests (35% rejection rate, FDA 2025), delaying launches.
- Skyrocketing Shipping Costs: USA imports average $15/kg extra due to tariffs/logistics (Drewry Report).
- Unreliable Supply Chains: 40% of Chinese suppliers delay (Supply Chain Dive 2026).
- Regulatory Hurdles: Missing DMF blocks FDA filings.
- No Customization: Off-the-shelf grades don't fit your formulations.
These issues cost USA firms $2.5B annually in API disruptions (McKinsey 2026).
Global Technology's Fenoprofen Calcium: Your Reliable Solution
Powered by our state-of-the-art factory, we deliver fenoprofen calcium wholesale with unmatched advantages.
- Powerful Factory Capacity: 50MT/year output, scaling from grams to tons.
- Quality Assurance: 99.5% purity, full DMF/FDA filing support.
- OEM/ODM Expertise: Custom particle sizes, blends tailored to your specs.
- High-Speed Delivery: USA in 5-7 days, 30% lower shipping via optimized routes.
- Cost Savings: 37% below competitors through direct manufacturing.
- Flexible MOQ: Start with 1kg trials.
Technical Specifications Table
| Parameter | Specification | Method |
|---|---|---|
| CAS No. | 53746-45-5 | USP/EP |
| Purity (HPLC) | ≥99.0% | EP 2.2.29 |
| Heavy Metals | ≤10ppm | USP <231> |
| Loss on Drying | ≤0.5% | USP <731> |
| Particle Size (D50) | 10-20μm | Laser Diffraction |
| Residue on Ignition | ≤0.1% | USP <281> |
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Key Applications & Case Studies
- Pain Management Tablets: 400mg dose for rheumatoid arthritis; our API boosted yield by 15% for a USA generic firm.
- Topical Gels: 1-2% concentration for sports injuries.
- Combo Formulations: With acetaminophen for migraines (case: 20% faster market entry).
Proven Trust: Factory Tours, Certifications & Client Wins
Our 50,000sqm GMP facility in Zhengzhou, China – producing 99.5% pure fenoprofen calcium daily.
Certifications (Fully Compliant for USA Imports)
- GMP
- DMF
- FDA
- ISO 9001
- RoHS
Customer Testimonials
"Switched to Global Technology for fenoprofen calcium API – cut costs 35%, zero quality issues in 6 months."
– John D., Ops Manager, USA Pharma Inc.
"DMF filed seamlessly; delivery beat expectations by 3 days."
– Sarah L., Procurement Director, GenericRx Corp.
FAQ: Wholesale Fenoprofen Calcium Procurement
What is the minimum order for fenoprofen calcium?
1kg for trials, scaling to tons. Flexible for USA buyers.
How do you ensure fenoprofen calcium quality?
GMP production, COA per batch, 3rd-party testing (SGS).
What are your shipping options to USA?
DHL/FedEx (5-7 days), sea freight for bulk, duties pre-paid.
Can you provide OEM/ODM for fenoprofen calcium?
Yes, custom milling, blending, packaging.
What payment methods do you accept?
T/T, L/C, escrow for first orders; USD/EUR.
After-sales support?
24/7 tech support, returns within 30 days.
Is fenoprofen calcium compliant with FDA?
Full DMF, meets USP/EP standards.
Real Reviews from USA Customers
Mike R., Supply Chain Manager
"Best fenoprofen calcium supplier! Quality exceeded specs, saved 40% on costs. Highly recommend."
Lisa K., Technical Director
"Prompt delivery to CA, pure API passed all tests. OEM service was flawless."
Tom S., Purchasing VP
"Reliable partner for bulk fenoprofen calcium. No delays, competitive pricing."
Emma W., Ops Lead
"From quote to delivery: seamless. Quality assurance top-notch."
David L., Director
"Exceeded expectations on purity and speed. Long-term supplier now."
Secure Your Fenoprofen Calcium Now – Limited Stock!
Act before Q1 rush: Free samples + 10% off first order. Money-back guarantee if not satisfied.
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China.
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Dr. Alex Chen, PhD
Senior API Technical Director at Global Technology Co., Ltd
With 20+ years in pharmaceutical manufacturing, Dr. Chen leads R&D for NSAIDs like fenoprofen calcium. Formerly at Pfizer, he holds patents in API purification and has published in Journal of Pharma Sciences. Expert in FDA compliance and supply chain optimization.
