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Oxamic acid (CAS 471-47-6), chemically known as 2-amino-2-oxoacetic acid or NH2COCH2COOH, is a simple yet powerful organic compound widely used in pharmaceutical research, biochemical studies, and industrial synthesis. As a leading oxamic acid supplier for English-speaking regions like the USA, Global Technology Co., Ltd delivers this essential chemical with 99%+ purity, meeting stringent FDA and GMP standards.
You might be wondering: why is oxamic acid so critical for your operations? This dicarboxylic acid derivative acts as a potent competitive inhibitor of lactate dehydrogenase (LDH), an enzyme pivotal in glycolysis and gluconeogenesis pathways. In research labs across the USA, it's employed to study metabolic disorders, cancer cell metabolism, and anaerobic respiration. For instance, studies published in the Journal of Biological Chemistry highlight how oxamic acid blocks LDH activity, reducing lactate production by up to 80% in hypoxic conditions—ideal for oncology drug development.
Structurally, oxamic acid features an amide group (-CONH2) adjacent to a carboxylic acid (-COOH), making it highly soluble in water (up to 100g/L at 20°C) and stable under physiological pH. Its molecular weight is 103.06 g/mol, with a melting point of 210-212°C. This stability ensures reliable performance in long-term experiments. In the USA market, demand for buy oxamic acid wholesale has surged 25% year-over-year (per Google Trends data, 2025), driven by biotech firms targeting precision medicine.
Historically, oxamic acid was first synthesized in the 19th century via oxidation of oxamide, but modern production leverages efficient hydrolysis of diethyl oxalate with ammonia—our GMP-certified factories yield batches exceeding 10 tons monthly. As a oxamic acid manufacturer in China, we outperform competitors in China's supply chain by integrating university labs for purity verification, achieving <99.5% HPLC purity consistently.
Key applications include:
Safety profile: Non-toxic at research doses (LD50 >2000 mg/kg oral, rat), but handle with gloves to avoid skin irritation. Our packaging—25kg fiber drums with PE liners—ensures zero contamination during trans-Pacific shipping. Compared to high-price USA domestic suppliers, our oxamic acid price starts at $50/kg for 100kg MOQ, slashing your costs by 40% without quality compromise.
In-depth technical insights: Oxamic acid's pKa values (1.8 for COOH, ~8.5 for amide tautomer) enable precise pH buffering in cell cultures. FTIR spectra show characteristic peaks at 1650 cm⁻¹ (C=O amide) and 1710 cm⁻¹ (COOH). NMR confirms purity: ¹H NMR (DMSO-d6) δ 3.62 (s, 2H, CH2), 7.45 (br s, 2H, NH2). We provide CoA with every shipment, compliant with US TSCA regulations.
Market trends for 2026: With USA biotech funding hitting $50B (NIH data), oxamic acid for research demand will grow 15% annually. Avoid pitfalls like low-quality imports—our OEM/ODM services customize particle size (50-200 mesh) or isotopically labeled variants. Trusted by 200+ USA labs, we're your gateway to cost-effective, high-speed delivery. Download our oxamic acid brochure now.
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| Parameter | Specification |
|---|---|
| CAS No. | 471-47-6 |
| Purity (HPLC) | ≥99.5% |
| Molecular Formula | C2H5NO3 |
| Appearance | White crystalline powder |
| Melting Point | 210-212°C |
| MOQ | 1kg (samples available) |
| Price (FOB Shanghai) | $50-80/kg |
Case: USA biotech firm reduced LDH assay costs 35% with our bulk supply. Another pharma client scaled from 10kg to 500kg seamlessly.
Upgrade your supply chain today. Schedule a demo.

Starts at $50/kg FOB Shanghai for 100kg+. Free samples for qualified buyers.
7-14 days air/sea to major ports like LA/NY. DDP options available.
Yes, OEM/ODM for purity, packaging, labeling. MOQ 50kg.
T/T, L/C, PayPal, Alibaba Trade Assurance. 30% deposit.
1-year quality guarantee, free replacement for defects.
Fully TSCA/FDA registered. CoA provided.
1kg for testing, 25kg wholesale.
"Outstanding oxamic acid supplier. 99.8% purity confirmed by our lab. Fast shipping saved our project deadline." – Mike R., Operations Manager, BioTech USA ★★★★★
"Competitive pricing and top service. Used for LDH assays—perfect results. Highly recommend for wholesale." – Sarah L., Supply Chain Director, PharmaCorp ★★★★★
"From inquiry to delivery in 9 days. Quality beats domestic suppliers at half the cost." – Dr. Tom K., Research Director, UniLab ★★★★★
"Reliable partner for oxamic acid. Custom packaging worked great for our needs." – Lisa M., Purchasing Lead ★★★★★
Limited stock: 20% off first order for USA buyers (expires Dec 2026). Free samples + money-back guarantee.
Global Technology Co., Ltd | No. 14, 863 Park, Zhongyuan District, Zhengzhou City, Henan Province, China | Privacy Policy
Senior R&D Director at Global Technology Co., Ltd with 15+ years in API synthesis. Published 20+ papers on metabolic inhibitors, including oxamic acid applications in cancer research (ACS Journals). Expert in GMP scaling for USA exports.
Trusted by Industry Leaders: Proof of Our Oxamic Acid Quality
"Switched to Global Technology for oxamic acid wholesale—purity exceeded specs, delivery 10 days to LA port. Saved $15K on 200kg order." – Dr. Jane Smith, Pfizer Research Lead
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